Phase 2 Schizophrenia Clinical Trials

42 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 42 trials

Recruiting
Phase 2

Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate

SchizophreniaSchizo Affective DisorderSymptom, Cognitive
National Cheng-Kung University Hospital90 enrolled1 locationNCT06340789
Recruiting
Phase 2

A Study of Brenipatide in Adult Participants With Schizophrenia

Schizophrenia
Eli Lilly and Company450 enrolled102 locationsNCT07410507
Recruiting
Phase 2

Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia

Schizophrenia
Neurocrine Biosciences120 enrolled5 locationsNCT07288333
Recruiting
Phase 2

Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia

Schizophrenia
Novartis Pharmaceuticals142 enrolled7 locationsNCT07467993
Recruiting
Phase 2

Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia

Schizophrenia
University of California, Los Angeles40 enrolled1 locationNCT05778591
Recruiting
Phase 1Phase 2

Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine

SchizophreniaMajor Depressive DisorderBipolar I Disorder
Mapi Pharma Ltd.24 enrolled6 locationsNCT07185815
Recruiting
Phase 2

A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia

Schizophrenia
MapLight Therapeutics500 enrolled5 locationsNCT07459647
Recruiting
Phase 1Phase 2

Acetazolamide for Treatment Resistant Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD60 enrolled2 locationsNCT04887792
Recruiting
Phase 2

Synbiotic Compound to Reduce Symptoms of Schizophrenia

SchizophreniaSchizoaffective Disorder
Sheppard Pratt Health System68 enrolled1 locationNCT04226898
Recruiting
Phase 1Phase 2

Ocrelizumab for Psychosis by Autoimmunity

SchizophreniaSchizo-Affective Type of Psychosis
The Methodist Hospital Research Institute40 enrolled1 locationNCT03971487
Recruiting
Phase 2

Monotherapy of an NMDA Enhancer for Schizophrenia

Schizophrenia
China Medical University Hospital80 enrolled1 locationNCT04745143
Recruiting
Phase 2

Dual Modulation of Sigma-1 and NMDA Receptors in the Treatment of Schizophrenia

Schizophrenia
China Medical University Hospital90 enrolled1 locationNCT06574360
Recruiting
Phase 2

Early Intervention of Prodromal Schizophrenia Using an NMDA Enhancer

Prodromal Schizophrenia
China Medical University Hospital48 enrolled1 locationNCT05052853
Recruiting
Phase 2

Combination of NMDA-enhancing and Anti-inflammatory Treatments for Ultra-resistant Schizophrenia

Schizophrenia
China Medical University Hospital80 enrolled1 locationNCT05240976
Recruiting
Phase 1Phase 2

Tolerability of MDMA in Schizophrenia

Schizophrenia
Anya Bershad, MD, PhD20 enrolled1 locationNCT05770375
Recruiting
Phase 1Phase 2

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD160 enrolled1 locationNCT03794076
Recruiting
Phase 2

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Inpatient Adults With Schizophrenia

Schizophrenia
MapLight Therapeutics300 enrolled25 locationsNCT07038876
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Phase 2

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

Schizophrenia
AbbVie268 enrolled7 locationsNCT07145918
Recruiting
Phase 2

Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder

SchizophreniaAlcoholismSchizophrenia Disorders+5 more
Anders Fink-Jensen, MD, DMSci108 enrolled2 locationsNCT06939088