Phase 2 Schizophrenia Clinical Trials

24 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 24 trials

Recruiting
Phase 1Phase 2

Tolerability of MDMA in Schizophrenia

Schizophrenia
Anya Bershad, MD, PhD20 enrolled1 locationNCT05770375
Recruiting
Phase 1Phase 2

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD160 enrolled1 locationNCT03794076
Recruiting
Phase 2

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Inpatient Adults With Schizophrenia

Schizophrenia
MapLight Therapeutics300 enrolled25 locationsNCT07038876
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Phase 2

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

Schizophrenia
AbbVie268 enrolled7 locationsNCT07145918
Recruiting
Phase 2

Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder

SchizophreniaAlcoholismSchizophrenia Disorders+5 more
Anders Fink-Jensen, MD, DMSci108 enrolled2 locationsNCT06939088
Recruiting
Phase 2

Study of ALTO-101 in Patients With Schizophrenia

Cognitive ImpairmentSchizophrenia
Alto Neuroscience82 enrolled14 locationsNCT06502964
Recruiting
Phase 1Phase 2

Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine

SchizophreniaMajor Depressive Disorder (MDD)Bipolar 1 Disorder
Mapi Pharma Ltd.24 enrolled3 locationsNCT07185815
Recruiting
Phase 2

A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

Cognitive Impairment Associated With Schizophrenia (CIAS)
Kynexis B.V.150 enrolled13 locationsNCT07191483
Recruiting
Phase 2Phase 3

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

Cognitive ImpairmentMitochondrial AlterationSchizophrenia and Related Disorders
Mclean Hospital100 enrolled3 locationsNCT06191965
Recruiting
Phase 2

Sex Differences in NMDA-enhancing Treatment of Schizophrenia

Schizophrenia
China Medical University Hospital90 enrolled1 locationNCT07122895
Recruiting
Phase 2

A Clinical Trial to Evaluate the Safety and Efficacy of Olanzapine Titration Schedule in Patients With Schizophrenia

Schizophrenia
Boryung Pharmaceutical Co., Ltd120 enrolled2 locationsNCT06821945
Recruiting
Phase 2

Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia

Schizophrenia
University of California, Los Angeles40 enrolled1 locationNCT05778591
Recruiting
Phase 1Phase 2

Acetazolamide for Treatment Resistant Schizophrenia

SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD60 enrolled2 locationsNCT04887792
Recruiting
Phase 2

Enhancing Social Skills in Schizophrenia Spectrum Disorders - Oxytocin as add-on to Psychosocial Treatment

Schizophrenia Spectrum Disorders (SSD)
Central Institute of Mental Health, Mannheim98 enrolled1 locationNCT06881810
Recruiting
Phase 2

NMDA-enhancing Treatment for Cognitive Dysfunction of Schizophrenia

Schizophrenia
China Medical University Hospital90 enrolled1 locationNCT06021197
Recruiting
Phase 2

Combination of NMDA-enhancing and Anti-inflammatory Treatments for Schizophrenia

Schizophrenia
China Medical University Hospital60 enrolled1 locationNCT04917302
Recruiting
Phase 2

Combination of NMDA-enhancing and Antioxidant Treatments for Schizophrenia

Schizophrenia
China Medical University Hospital90 enrolled1 locationNCT04959201
Recruiting
Phase 2

A Randomized Controlled Trial With Rituximab for Psychotic Disorder in Adults

Schizophrenia Spectrum and Other Psychotic Disorders
Region Örebro County120 enrolled1 locationNCT05622201
Recruiting
Phase 2

Dual Modulation of Sigma-1 and NMDA Receptors in the Treatment of Schizophrenia

Schizophrenia
China Medical University Hospital90 enrolled1 locationNCT06574360