Phase 4 Schizophrenia Clinical Trials
26 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 26 trials
Recruiting
Phase 4
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled22 locationsNCT07105111
Recruiting
Phase 4
A Study to Evaluate the Effect of KarXT on Urological Safety
Schizophrenia
Bristol-Myers Squibb60 enrolled13 locationsNCT07221877
Recruiting
Phase 4
Bazedoxifene -Treatment for Women With Schizophrenia
SchizophreniaSchizo Affective DisorderSchizophreniform Disorders
The Alfred160 enrolled1 locationNCT04113993
Recruiting
Phase 4
Anti-Inflammatory Challenge in Schizophrenia
Schizophrenia
Emory University60 enrolled2 locationsNCT05823532
Recruiting
Phase 4
Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia
SchizophreniaSchizo Affective Disorder
University of Massachusetts, Worcester50 enrolled1 locationNCT06174116
Recruiting
Phase 4
CLOZAPINE Response in Biotype-1
SchizophreniaSchizoaffective DisorderBipolar 1 Disorder
University of Texas Southwestern Medical Center524 enrolled5 locationsNCT04580134
Recruiting
Phase 4
Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial
SchizophreniaSchizoaffective Disorder
New York State Psychiatric Institute280 enrolled7 locationsNCT05208190
Recruiting
Phase 4
"Extended" (Alternate Day) Antipsychotic Dosing
Drug TherapySchizophrenia and Related DisordersAntipsychotic Agents+1 more
Centre for Addiction and Mental Health120 enrolled1 locationNCT04478838
Recruiting
Phase 4
Anticholinergic Deprescription in Schizophrenia
SchizophreniaSchizoaffective Disorder
Deepak K. Sarpal, M.D.105 enrolled1 locationNCT06562608
Recruiting
Phase 4
Biomarkers in Clozapine-responding Schizophrenia
SchizophreniaPsychosis
Jimmi Nielsen200 enrolled1 locationNCT05316883
Recruiting
Phase 4
The Effect of a Six Week Intensified Pharmacological Treatment for Schizophrenia Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Schizophrenia and Related DisordersEarly Treatment-Resistance
Dr. Inge Winter418 enrolled13 locationsNCT05958875
Not Yet Recruiting
Phase 4
The INTENSIFY Trial: The Effect of a Six-Week Intensified Pharmacological Treatment (Third-Line Medication) for Schizophrenia Compared to Treatment as Usual (Second-Line Medication) in Participants Who Did Not Respond to a First-Line Medication Treatment.
Schizophrenia
Lyell McEwin Hospital150 enrolled1 locationACTRN12625000327482
Recruiting
Phase 4
Safety and Tolerability of Open-Labeled Iloperidone in Adolescents
SchizophreniaBipolar I Disorder
Vanda Pharmaceuticals100 enrolled9 locationsNCT05648591
Recruiting
Phase 4
Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia
SchizophreniaSchizoaffective Disorder
Centre for Addiction and Mental Health30 enrolled1 locationNCT02639702
Recruiting
Phase 4
Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates
SchizophreniaTobacco SmokingParkinsonism+2 more
Corporal Michael J. Crescenz VA Medical Center10 enrolled1 locationNCT03495024
Terminated
Phase 4
Sofosbuvir/Velpatasvir and Mental Health Impact in people with Lived Experience and Hepatitis C infection - SMILE-C Trial
Schizophrenia
The University of Adelaide150 enrolled8 locationsACTRN12618001939280
Recruiting
Phase 4
The efficacy of Metformin as an adjunctive treatment to attenuate weight gain and metabolic syndrome in patients with schizophrenia or schizoaffective disorder newly commenced on clozapine
Schizophrenia
The University of Queensland86 enrolled7 locationsACTRN12617001547336
Completed
Phase 4
Quality of life (QoL) in patients on Abilify Maintena in the private setting.
Quality of LifeSchizophrenia
Dr. Benjamin Hadikusumo100 enrolled1 locationACTRN12617000211369
Terminated
Phase 4
What is the difference in the safety of Ketamine versus Propofol when used to sedate Acute Psychiatric/ Psychotic Patients who require Aeromedical Retrieval?
Personality DisorderAcute PsychosisDepression+3 more
CareFlight Limited400 enrolled1 locationACTRN12616001134415
Terminated
Phase 4
N-Acetyl Cysteine In Schizophrenia Resistant To Clozapine: A Double-Blind Randomised Placebo-Controlled Trial Targeting Negative Symptoms
Schizophrenia resistant to clozapine
The University of Melbourne168 enrolled8 locationsACTRN12615001273572