Phase 2 seizure Clinical Trials
14 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–14 of 14 trials
Recruiting
Phase 2
Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy
EpilepsySeizures, Epileptic
Supernus Pharmaceuticals, Inc.60 enrolled10 locationsNCT05518578
Recruiting
Phase 1Phase 2
A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
seizureEpilepsyDrug Resistant Epilepsy+2 more
NaviFUS Corporation8 enrolled3 locationsNCT06388707
Recruiting
Phase 2
Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases
Brain Metastases, AdultBrain Metastases From Non-small Cell Lung Cancer (NSCLC)Brain Metastases From Extra-cranial Solid Tumors+2 more
Ayal A. Aizer, MD150 enrolled1 locationNCT07130786
Recruiting
Phase 2
A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
seizureEpilepsyRefractory Focal Epilepsy+3 more
Rapport Therapeutics Inc.30 enrolled7 locationsNCT07219407
Recruiting
Phase 2
A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures
Neonatal EncephalopathyNeonatal SeizureSeizure Newborn+1 more
University of California, San Diego133 enrolled5 locationsNCT05610085
Recruiting
Phase 2
A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy
Pediatric Epileptic SyndromePartial-onset Seizures
Eisai Inc.100 enrolled49 locationsNCT04015141
Recruiting
Phase 2
SPN-817 Open-Label Extension Study in Adults With Focal Onset Seizures
Focal Onset Seizures
Supernus Pharmaceuticals, Inc.100 enrolled1 locationNCT07141329
Recruiting
Phase 2
PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest
SeizuresStatus EpilepticusHeart Arrest
University of California, San Francisco52 enrolled1 locationNCT06401707
Recruiting
Phase 2Phase 3
Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1)
Focal Seizure
Praxis Precision Medicines230 enrolled26 locationsNCT06999902
Recruiting
Phase 2
buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest
SeizuresStatus EpilepticusHypoxia-Ischemia, Brain+4 more
University of California, San Francisco30 enrolled1 locationNCT05851391
Recruiting
Phase 2
An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures
Focal Onset SeizurePrimary Generalized Epilepsy
Praxis Precision Medicines50 enrolled11 locationsNCT06908356
Recruiting
Phase 2
RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults with Focal Onset Seizures
Focal Onset Seizures
Supernus Pharmaceuticals, Inc.258 enrolled1 locationNCT06798896
Completed
Phase 2
Remi-Fent1 Study: A Comparison of Remifentanil and Fentanyl in Mechanically Ventilated Patients
Control refractory seizuresRespiratory failure
- issues with oxygenation or ventilationPrevent secondary brain injury+3 more
Arvind Rajamani100 enrolled1 locationACTRN12620000719932
Terminated
Phase 2
Study of PRAX-944 to Assess the Safety, Tolerability, PK, and Efficacy of Escalating Doses in Adults with Absence Seizures
Absence Seizures
Praxis Precision Medicines, Pty, Ltd.12 enrolled1 locationACTRN12618000961246