Skin Clinical Trials

5 recruiting

Skin Trials at a Glance

322 actively recruiting trials for skin are listed on ClinicalTrialsFinder across 6 cities in 48 countries. The largest study group is Not Applicable with 125 trials, with the heaviest enrollment activity in New York, Miami, and Houston. Lead sponsors running skin studies include Mayo Clinic, M.D. Anderson Cancer Center, and Alpha Tau Medical LTD..

Treatments under study

About Skin Clinical Trials

Looking for clinical trials for Skin? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Skin trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Skin clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 322 trials

Recruiting

Diagnosis and Treatment of Leishmania Infections

LeishmaniasisSkin Diseases, ParasiticEuglenozoa Infections+1 more
National Institute of Allergy and Infectious Diseases (NIAID)289 enrolled1 locationNCT00344188
Recruiting
Phase 2

Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System

Metastatic Skin Squamous Cell CarcinomaLocally Recurrent Skin Squamous Cell Carcinoma
National Cancer Institute (NCI)86 enrolled30 locationsNCT07042295
Recruiting
Phase 3

Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer

Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Eyelid Squamous Cell Carcinoma+17 more
National Cancer Institute (NCI)420 enrolled206 locationsNCT06568172
Recruiting
Phase 1Phase 2

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Melanoma+10 more
National Cancer Institute (NCI)16 enrolled26 locationsNCT05896839
Recruiting
Not Applicable

BEnefit of HYpnosis on Pain During Stitches in Emergency Room

Wound of Skin
University Hospital, Clermont-Ferrand180 enrolled1 locationNCT06497712
Recruiting
Phase 1Phase 2

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

Lung CancerMelanomaMetastatic Lung Cancer+2 more
Obsidian Therapeutics, Inc.208 enrolled9 locationsNCT06060613
Recruiting
Early Phase 1

Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin Disorders

Skin Diseases
Northwestern University30 enrolled1 locationNCT05649098
Recruiting
Phase 2

SHIELD: Sorafenib Hand-foot Syndrome Inhibition With Pre-Emptive Local Delivery of Topical Indomethacin

Hepato Cellular Carcinoma (HCC)Hand Foot Skin Syndrome
National Taiwan University Hospital39 enrolled1 locationNCT07560566
Recruiting

Clinical Observational Study on Changes in Skin Physiological Parameters Following Ablative and Non-Ablative Fractional Laser Treatment at Different Doses

Wound HealingSkin Barrier Function
ChinaNorm20 enrolled1 locationNCT07561242
Recruiting
Phase 1Phase 2

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

MelanomaNon-small Cell Lung CancerSquamous Cell Carcinoma (Skin)+2 more
AstraZeneca60 enrolled11 locationsNCT07115043
Recruiting
Not Applicable

Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.

Frequency and Type of Medical Adhesive-Related Skin InjuryNPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate)Clinician Acceptability of New NPWT Drape+2 more
Global Biomedical Technologies, LLC300 enrolled6 locationsNCT06717308
Recruiting
Not Applicable

Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

Melanoma (Skin Cancer)Renal Cell Carcinoma (Kidney Cancer)Breast Cancer (Triple Negative Breast Cancer (TNBC))
Jessica Mezzanotte Sharpe25 enrolled1 locationNCT07555210
Recruiting
Not Applicable

Evaluation of Fractional Ablative Laser Treatment for Skin Conditions

Skin Laxity
Sciton1,000 enrolled1 locationNCT05750901
Recruiting
Phase 2

Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia

Tardive Dyskinesia
Neurocrine Biosciences100 enrolled6 locationsNCT07365462
Recruiting
Phase 2Phase 3

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

Unresectable MelanomaCutaneous MelanomaMelanoma (Skin Cancer)+1 more
Linnaeus Therapeutics, Inc.135 enrolled9 locationsNCT06624644
Recruiting
Not Applicable

Study of a Peptide Cream's Effect on the Facial Skin Barrier Using a Side-by-Side Comparison

Skin Barrier FunctionSkin HydrationTopical Peptide Effects on Facial Skin Barrier Function
University of Split, School of Medicine30 enrolled1 locationNCT07548424
Recruiting
Phase 3

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

AlopeciaSkin DiseasesAreata Alopecia+3 more
Eli Lilly and Company595 enrolled127 locationsNCT05723198
Recruiting
Not Applicable

Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

Skin Laxity (Submental and Neck)Facial Skin LaxitySubmental Tissue Laxity
CLASSYS Inc.273 enrolled5 locationsNCT07229430
Recruiting
Not Applicable

Influence of Dressings on Skin pH Alterations in Simulated Skin Folds in Healthy Subjects

Skin Folds
Essity Hygiene and Health AB40 enrolled1 locationNCT07547488
Recruiting
Phase 2

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Advanced Colorectal CarcinomaAdvanced Anal CarcinomaAdvanced Biliary Tract Carcinoma+41 more
Mayo Clinic220 enrolled2 locationsNCT05969860