Phase 2 Skin Clinical Trials
66 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 66 trials
Recruiting
Phase 2
Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System
Metastatic Skin Squamous Cell CarcinomaLocally Recurrent Skin Squamous Cell Carcinoma
National Cancer Institute (NCI)86 enrolled30 locationsNCT07042295
Recruiting
Phase 1Phase 2
Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Melanoma+10 more
National Cancer Institute (NCI)16 enrolled26 locationsNCT05896839
Recruiting
Phase 1Phase 2
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
Lung CancerMelanomaMetastatic Lung Cancer+2 more
Obsidian Therapeutics, Inc.208 enrolled9 locationsNCT06060613
Recruiting
Phase 2
SHIELD: Sorafenib Hand-foot Syndrome Inhibition With Pre-Emptive Local Delivery of Topical Indomethacin
Hepato Cellular Carcinoma (HCC)Hand Foot Skin Syndrome
National Taiwan University Hospital39 enrolled1 locationNCT07560566
Recruiting
Phase 1Phase 2
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
MelanomaNon-small Cell Lung CancerSquamous Cell Carcinoma (Skin)+2 more
AstraZeneca60 enrolled11 locationsNCT07115043
Recruiting
Phase 2
Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia
Tardive Dyskinesia
Neurocrine Biosciences100 enrolled6 locationsNCT07365462
Recruiting
Phase 2Phase 3
A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma
Unresectable MelanomaCutaneous MelanomaMelanoma (Skin Cancer)+1 more
Linnaeus Therapeutics, Inc.135 enrolled9 locationsNCT06624644
Recruiting
Phase 2
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Advanced Colorectal CarcinomaAdvanced Anal CarcinomaAdvanced Biliary Tract Carcinoma+41 more
Mayo Clinic220 enrolled2 locationsNCT05969860
Recruiting
Phase 2
Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides
Mycosis FungoidesLocalized Skin Lesion
M.D. Anderson Cancer Center50 enrolled1 locationNCT03398161
Recruiting
Phase 2
Effects of Treatments on Atopic Dermatitis
DermatitisEczemaSkin Diseases, Genetic
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)130 enrolled1 locationNCT01631617
Recruiting
Phase 1Phase 2
Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)
Cutaneous Squamous Cell CarcinomaSkin Cancers - Squamous Cell Carcinoma
Falo, Louis, MD48 enrolled1 locationNCT05377905
Recruiting
Phase 1Phase 2
Early Phase Study of KESONOTIDE™in Participants With Solid Tumours
Breast CancerLung CancersOvarian Cancer+4 more
Filamon LTD80 enrolled3 locationsNCT06926075
Recruiting
Phase 1Phase 2
Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
Melanoma (Skin Cancer)HER2-low Hormone Receptor Positive Breast Cancer
Aminex Therapeutics, Inc.92 enrolled8 locationsNCT07287917
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+97 more
Mayo Clinic132 enrolled1 locationNCT05269381
Recruiting
Phase 1Phase 2
MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
Metastatic MelanomaMelanoma Stage IVMelanoma Stage III+1 more
Perspective Therapeutics300 enrolled13 locationsNCT05655312
Recruiting
Phase 2
EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers
Skin Squamous Cell CarcinomaMerkel Cell CarcinomaCutaneous Melanoma
Ohio State University Comprehensive Cancer Center100 enrolled1 locationNCT06223659
Recruiting
Phase 2
Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory Melanoma
MelanomaMelanoma Stage IVMelanoma (Skin)+1 more
University of California, Irvine14 enrolled1 locationNCT06771544
Recruiting
Phase 2
A Phase II Clinical Trial on Neo-adjuvant Pembrolizumab in Patients With pT3b-T4a/b cN0M0 Melanoma.
Melanoma (Skin Cancer)
Universitair Ziekenhuis Brussel49 enrolled1 locationNCT07448831
Recruiting
Phase 2
Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG)
Pyoderma GangrenosumWound HealSkin Diseases+2 more
Oregon Health and Science University17 enrolled2 locationsNCT06563323
Recruiting
Phase 2
Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder
Cancer of the BreastCancerAdjustment Disorder+8 more
Psyence Australia Pty Ltd87 enrolled3 locationsNCT07072728