Phase 3 Sleep Clinical Trials
34 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 34 trials
Recruiting
Phase 3
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy
ObesityObstructive Sleep Apnea
Amgen250 enrolled47 locationsNCT07225686
Recruiting
Phase 3
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy
Obstructive Sleep Apnea
Amgen250 enrolled38 locationsNCT07226765
Recruiting
Phase 3
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
ObesityOverweightSleep Apnea, Obstructive
Eli Lilly and Company800 enrolled123 locationsNCT07369011
Recruiting
Phase 3
A Study of XW003 in Obese Participants With Obstructive Sleep Apnea But Not Receive Positive Airway Pressure Therapy
ObesityOSA - Obstructive Sleep Apnea
Hangzhou Sciwind Biosciences Co., Ltd.140 enrolled1 locationNCT07387094
Recruiting
Phase 3
A Study of XW003 in Obese Participants With Obstructive Sleep Apnea Receiving Positive Airway Pressure Therapy
ObesityOSA - Obstructive Sleep Apnea
Hangzhou Sciwind Biosciences Co., Ltd.140 enrolled1 locationNCT07434050
Recruiting
Phase 3
Repurposing Low-Dose Clonidine for PTSD in Veterans
SleepPTSDPosttraumatic Stress Disorder
Wake Forest University Health Sciences32 enrolled1 locationNCT04877093
Recruiting
Phase 2Phase 3
Pharmacokinetic, Efficacy, Safety and Tolerability Study of a Single Dose of Acoziborole in g-HAT Paediatric Patients
Trypanosomiasis, AfricanTrypanosoma Brucei Gambiense; InfectionSleeping Sickness
Drugs for Neglected Diseases35 enrolled6 locationsNCT05433350
Recruiting
Phase 3
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
Axsome Therapeutics, Inc.508 enrolled13 locationsNCT07484217
Recruiting
Phase 3
Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)
Sleep Wake DisordersSleep Disorders, Circadian RhythmChronobiology Disorders
Vanda Pharmaceuticals70 enrolled17 locationsNCT04652882
Recruiting
Phase 3
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
Shift-work DisorderExcessive Sleepiness
Axsome Therapeutics, Inc.520 enrolled40 locationsNCT06568367
Recruiting
Phase 3
A Phase III Study Evaluating the Efficacy and Safety of HRS9531 Injection in Subjects With Obstructive Sleep Apnea (OSA) and Obesity
Bstructive Sleep Apnea (OSA) and Obesity
Fujian Shengdi Pharmaceutical Co., Ltd.140 enrolled1 locationNCT06974851
Recruiting
Phase 2Phase 3
Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
CancerDepressionSleep+2 more
M.D. Anderson Cancer Center188 enrolled1 locationNCT05474846
Recruiting
Phase 3
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
Malignant Female Reproductive System NeoplasmAnxietySleep Disturbance+2 more
Wake Forest University Health Sciences160 enrolled2 locationsNCT05625360
Recruiting
Phase 3
Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients
Postoperative DeliriumPreoperative Sleep Disorder
Xijing Hospital686 enrolled1 locationNCT06619912
Recruiting
Phase 3
A Study of IBI362 in Chinese Subjects With Obstructive Sleep Apnea and BMI≥28 kg/m2
ObesitySleep ApneaObstructive
Innovent Biologics (Suzhou) Co. Ltd.260 enrolled1 locationNCT06931028
Recruiting
Phase 3
Lemborexant Treatment of Insomnia Linked to Epilepsy
EpilepsySleep
University of Manitoba26 enrolled2 locationsNCT06262594
Recruiting
Phase 3
Evaluating the Effects of Tasimelteon Vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD) and the CRY1Δ11 Variant
Sleep Wake DisordersSleep Disorders, Circadian RhythmChronobiology Disorders+1 more
Vanda Pharmaceuticals60 enrolled1 locationNCT06701396
Recruiting
Phase 3
OROPHARYNGEAL MYOFUNCTIONAL THERAPY IN OBSTRUCTIVE SLEEP APNEA
Obstructive Sleep Apnea
Instituto de Investigación Marqués de Valdecilla30 enrolled1 locationNCT06681974
Recruiting
Phase 3
Lemborexant on Improving Sleep Quality Among Hospital Rotating Shift Workers
Sleep
Phramongkutklao College of Medicine and Hospital50 enrolled1 locationNCT06496282
Recruiting
Phase 3
MELODY Trial: A 12-week randomised controlled trial of adjunctive melatonin or digital cognitive behavioural therapy for insomnia, or placebo to improve depressive symptoms in young adults with mood disorders
Bipolar Disorder Type IIDepressionSleep Disturbance
The University of Sydney660 enrolled1 locationACTRN12624000017527