Phase 4 Sleep Clinical Trials

42 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 42 trials

Recruiting
Phase 4

Lemborexant in Delayed Sleep Phase Syndrome

Delayed Sleep Phase Syndrome
University of California, San Francisco15 enrolled1 locationNCT06874855
Recruiting
Phase 4

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Sleep DisturbanceAtopic Dermatitis
Northwestern University40 enrolled1 locationNCT05042258
Recruiting
Phase 4

Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty

SleepKnee Osteoarthritis
University of Miami64 enrolled1 locationNCT06902285
Recruiting
Phase 4

Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease

SleepAlzheimer DiseaseInsomnia Disorder
University Hospital, Montpellier62 enrolled1 locationNCT05924425
Recruiting
Phase 4

The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study

surgical stress responsePostoperative FatiguePostoperative Sleep Disturbances
Ziekenhuis Oost-Limburg102 enrolled1 locationNCT06480539
Recruiting
Phase 4

Endotype DIrected Treatment for OSA in Down Syndrome

Down SyndromeObstructive Sleep Apnea (OSA)
University of Arizona200 enrolled5 locationsNCT07280468
Recruiting
Phase 4

Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)

Obstructive Sleep Apnea of Adult
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran50 enrolled1 locationNCT06380491
Recruiting
Phase 4

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

Sleep-Disordered BreathingAble Bodied
VA Office of Research and Development200 enrolled1 locationNCT04118387
Recruiting
Phase 4

Impact GLP-1 Agonists Following Bariatric

Diabetes MellitusMetabolic SyndromeHypertension+2 more
University of Missouri-Columbia150 enrolled1 locationNCT06132477
Recruiting
Phase 4

Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics

Obstructive Sleep Apnea
Children's Hospital Medical Center, Cincinnati120 enrolled1 locationNCT04991389
Recruiting
Phase 4

Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

Pain, PostoperativeSleep-Disordered BreathingTonsillitis+2 more
Duke University440 enrolled1 locationNCT06576830
Recruiting
Phase 4

Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

Sleep ApneaSpinal Cord Injury
John D. Dingell VA Medical Center100 enrolled1 locationNCT02922894
Recruiting
Phase 4

Sleep Apnea in Elderly

Elderly adultsSleep Apnea
VA Office of Research and Development100 enrolled1 locationNCT02703220
Recruiting
Phase 4

CPAP Effect on the Polycythemia in Patients With Obstructive Sleep Apnea

Sleep Apnea, ObstructivePolycythemia
Hospital Universitario Ramon y Cajal182 enrolled1 locationNCT06089603
Recruiting
Phase 4

Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study

Sleep Apnea
Yale University164 enrolled2 locationsNCT05612594
Recruiting
Phase 4

The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Interventional)

Ischemic Stroke, AcuteSleep Disorders, Circadian Rhythm
Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health80 enrolled1 locationNCT05247125
Recruiting
Phase 4

Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality

Knee Replacement Surgeryhip replacement surgerySleep Quality+3 more
Peking University First Hospital154 enrolled2 locationsNCT05950646
Recruiting
Phase 4

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

Sleep Initiation and Maintenance DisordersStress Disorders, Posttraumatic
VA Office of Research and Development190 enrolled4 locationsNCT03642028
Recruiting
Phase 4

HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men

Sleep-Disordered Breathing
University of Zurich270 enrolled1 locationNCT06498531
Recruiting
Phase 4

Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery

EsketamineDexmedetomidineAdults+2 more
Peking University First Hospital476 enrolled1 locationNCT06859892