Phase 4 Sleep Clinical Trials

40 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 40 trials

Recruiting
Phase 4

Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty

SleepKnee Osteoarthritis
University of Miami64 enrolled1 locationNCT06902285
Recruiting
Phase 4

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Sleep DisturbanceAtopic Dermatitis
Northwestern University40 enrolled1 locationNCT05042258
Recruiting
Phase 4

Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease

SleepAlzheimer DiseaseInsomnia Disorder
University Hospital, Montpellier62 enrolled1 locationNCT05924425
Recruiting
Phase 4

The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study

Postoperative FatiguePostoperative Sleep Disturbances
Ziekenhuis Oost-Limburg102 enrolled1 locationNCT06480539
Recruiting
Phase 4

Endotype DIrected Treatment for OSA in Down Syndrome

Down SyndromeObstructive Sleep Apnea (OSA)
University of Arizona200 enrolled5 locationsNCT07280468
Recruiting
Phase 4

Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)

Obstructive Sleep Apnea of Adult
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran50 enrolled1 locationNCT06380491
Recruiting
Phase 4

Impact GLP-1 Agonists Following Bariatric

Diabetes MellitusMetabolic SyndromeHypertension+2 more
University of Missouri-Columbia150 enrolled1 locationNCT06132477
Recruiting
Phase 4

Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics

Obstructive Sleep Apnea
Children's Hospital Medical Center, Cincinnati120 enrolled1 locationNCT04991389
Recruiting
Phase 4

Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

Pain, PostoperativeSleep-Disordered BreathingTonsillitis+2 more
Duke University440 enrolled1 locationNCT06576830
Recruiting
Phase 4

Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

Sleep ApneaSpinal Cord Injury
John D. Dingell VA Medical Center100 enrolled1 locationNCT02922894
Recruiting
Phase 4

Sleep Apnea in Elderly

Sleep Apnea
VA Office of Research and Development100 enrolled1 locationNCT02703220
Recruiting
Phase 4

CPAP Effect on the Polycythemia in Patients With Obstructive Sleep Apnea

Sleep Apnea, ObstructivePolycythemia
Hospital Universitario Ramon y Cajal182 enrolled1 locationNCT06089603
Recruiting
Phase 4

Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study

Sleep Apnea
Yale University164 enrolled2 locationsNCT05612594
Recruiting
Phase 4

The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Interventional)

Ischemic Stroke, AcuteSleep Disorders, Circadian Rhythm
Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health80 enrolled1 locationNCT05247125
Recruiting
Phase 4

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

Sleep Initiation and Maintenance DisordersStress Disorders, Posttraumatic
VA Office of Research and Development190 enrolled4 locationsNCT03642028
Recruiting
Phase 4

HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men

Sleep-Disordered Breathing
University of Zurich270 enrolled1 locationNCT06498531
Recruiting
Phase 4

Lemborexant in Delayed Sleep Phase Syndrome

Delayed Sleep Phase Syndrome
University of California, San Francisco15 enrolled1 locationNCT06874855
Recruiting
Phase 4

Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery

EsketamineDexmedetomidineAdults+2 more
Peking University First Hospital476 enrolled1 locationNCT06859892
Recruiting
Phase 4

Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery

DexmedetomidineSleep Wake DisordersEsketamine and the Quality of Recovery
Nanjing First Hospital, Nanjing Medical University180 enrolled2 locationsNCT06778811
Recruiting
Phase 4

Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea

Sleep ApneaChronic Nasal Congestion
University of South Florida52 enrolled1 locationNCT02630121