Phase 2 Soft Tissue Sarcoma Clinical Trials
56 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 56 trials
Recruiting
Phase 2
Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial
Metastatic Alveolar Soft Part SarcomaAdvanced Soft Tissue SarcomaAdvanced Alveolar Soft Part Sarcoma+2 more
National Cancer Institute (NCI)27 enrolled13 locationsNCT05333458
Recruiting
Phase 2
Toripalimab Combined With CAV/IE Regimen
Soft Tissue Sarcoma
Sun Yat-sen University134 enrolled1 locationNCT04589741
Recruiting
Phase 2
5-Day Preoperative Radiation for Soft Tissue Sarcoma
Soft Tissue Sarcoma
Stanford University75 enrolled1 locationNCT06087861
Recruiting
Phase 1Phase 2
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
Breast CancerOvarian CancerProstate Cancer+6 more
University of Florida29 enrolled1 locationNCT05000294
Recruiting
Phase 2
A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.
Soft Tissue Sarcoma
Institut Claudius Regaud48 enrolled11 locationsNCT06022159
Recruiting
Phase 1Phase 2
The Combination of Radiotherapy, Chemotherapy and Immunotherapy in High-Risk Localized Soft Tissue Sarcoma
High-Risk Localized Soft Tissue Sarcoma
Fudan University52 enrolled1 locationNCT05774275
Recruiting
Phase 2
Cryoablation Plus Camrelizumab for Advanced Soft Tissue Sarcoma
OsteosarcomaSoft Tissue Sarcoma (STS)
Sun Yat-sen University57 enrolled1 locationNCT07602049
Recruiting
Phase 2
SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma
Soft Tissue Sarcoma
M.D. Anderson Cancer Center50 enrolled1 locationNCT07049848
Recruiting
Phase 1Phase 2
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Solid Tumor+19 more
St. Jude Children's Research Hospital90 enrolled10 locationsNCT04901702
Recruiting
Phase 1Phase 2
Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma
Metastatic Soft Tissue SarcomaMetastatic LeiomyosarcomaAdvanced Soft Tissue Sarcoma+5 more
National Cancer Institute (NCI)74 enrolled1 locationNCT06498648
Recruiting
Phase 2
Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma
Soft Tissue Sarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University25 enrolled1 locationNCT07243626
Recruiting
Phase 2
Phase 2 Trial of Zanzalintinib and Pembrolizumab in Select Subtypes of Advanced/Metastatic Soft-tissue Sarcoma
Soft Tissue SarcomaPembrolizumabPhase 2+2 more
M.D. Anderson Cancer Center20 enrolled1 locationNCT07283731
Recruiting
Phase 1Phase 2
Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma
Soft Tissue SarcomaSarcomaSarcoma,Soft Tissue+1 more
Memorial Sloan Kettering Cancer Center98 enrolled1 locationNCT04577014
Recruiting
Phase 2
Agnostic Therapy in Rare Solid Tumors
Cancer of Unknown PrimarySoft Tissue SarcomaCholangiocarcinoma+38 more
Instituto do Cancer do Estado de São Paulo28 enrolled8 locationsNCT06638931
Recruiting
Phase 2
Efficacy and Safety of Cadonilimab Plus Anlotinib in Advanced STS That Failed the Previous First-line Standard Treatment
Soft Tissue Sarcoma
Second Affiliated Hospital, School of Medicine, Zhejiang University27 enrolled1 locationNCT05926700
Recruiting
Phase 2
Cirtuvivint in Selected Advanced Soft-Tissue Sarcomas
Soft Tissue Sarcoma (STS)
Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas25 enrolled1 locationNCT07032285
Recruiting
Phase 2
Preoperative 5-Day Radiotherapy for Soft Tissue Sarcoma
Soft Tissue Sarcoma
Medical University of South Carolina40 enrolled1 locationNCT06905132
Recruiting
Phase 2
Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma
Soft Tissue SarcomaLeiomyosarcoma of Ovary
Italian Sarcoma Group100 enrolled17 locationsNCT04383119
Recruiting
Phase 1Phase 2
Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
Colorectal, CancerResectable SarcomaMetastatic Malignant Neoplasm in the Lung+3 more
Roswell Park Cancer Institute99 enrolled1 locationNCT03965234
Recruiting
Phase 2
IVIM & OLINK in Sarcoma
Soft Tissue Sarcoma
University Health Network, Toronto145 enrolled1 locationNCT05950594