Phase 2 Solid Tumor, Adult Clinical Trials

39 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 39 trials

Recruiting
Phase 1Phase 2

GT201 Injection For The Treatment Of Advanced Solid Tumors

Solid Tumor, Adult
Grit Biotechnology18 enrolled4 locationsNCT06144671
Recruiting
Phase 1Phase 2

Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated Ca

Solid Tumor, Adult
Virginia Commonwealth University83 enrolled1 locationNCT03919292
Recruiting
Phase 1Phase 2

A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Solid Tumor, Adult
BioInvent International AB197 enrolled25 locationsNCT04219254
Recruiting
Phase 1Phase 2

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

CancerSolid Tumor, AdultRefractory Cancer+1 more
Immatics US, Inc.375 enrolled21 locationsNCT03686124
Recruiting
Phase 1Phase 2

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

NSCLCSolid Tumor, AdultMesothelioma
Vivace Therapeutics, Inc434 enrolled12 locationsNCT04665206
Recruiting
Phase 1Phase 2

First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

Solid Tumor, Adult
DualityBio Inc.360 enrolled36 locationsNCT06554795
Recruiting
Phase 1Phase 2

COAST Therapy in Advanced Solid Tumors and Prostate Cancer

Solid Tumor, AdultProstate Cancer Recurrent
Medical University of South Carolina76 enrolled1 locationNCT05036226
Recruiting
Phase 1Phase 2

A Study of ATTR-01 in Participants With Select Epithelial Solid Tumours

Solid Tumor, Adult
Accession Therapeutics Limited72 enrolled7 locationsNCT06977737
Recruiting
Phase 1Phase 2

Study of AK119 Combined With AK112 in Patients With Advanced Solid Tumors

Solid Tumor, Adult
Akeso87 enrolled1 locationNCT05689853
Recruiting
Phase 1Phase 2

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

Metastatic Solid TumorSolid Tumor, AdultUnresectable Solid Tumor+1 more
Frontier Medicines Corporation403 enrolled26 locationsNCT06244771
Recruiting
Phase 1Phase 2

64Cu-GRIP B in Patients With Advanced Malignancies

Prostate CancerAdvanced Solid TumorSolid Tumor, Adult+3 more
Rahul Aggarwal91 enrolled1 locationNCT05888532
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Solid Tumor, Adult
A2 Biotherapeutics Inc.474 enrolled12 locationsNCT06051695
Recruiting
Phase 1Phase 2

Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

SarcomaSolid Tumor, AdultSolid Tumor, Childhood
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins39 enrolled4 locationsNCT03465592
Recruiting
Phase 2

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Solid TumorSolid Tumor, AdultRectal Adenocarcinoma+2 more
Memorial Sloan Kettering Cancer Center200 enrolled10 locationsNCT04165772
Recruiting
Phase 1Phase 2

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

Solid Tumor, Adult
Corbus Pharmaceuticals Inc.348 enrolled41 locationsNCT06265727
Recruiting
Phase 2Phase 3

HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma

Solid Tumor, AdultAdvanced Intrahepatic Cholangiocarcinoma
Hutchmed235 enrolled1 locationNCT04353375
Recruiting
Phase 1Phase 2

Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors

Breast CancerOvarian CancerProstate Cancer+3 more
Acerand Therapeutics (Shanghai) Limited298 enrolled14 locationsNCT06380660
Recruiting
Phase 1Phase 2

Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab

Solid Tumor, Adult
Linnaeus Therapeutics, Inc.200 enrolled10 locationsNCT04130516
Recruiting
Phase 2

Patritumab Deruxtecan in Patients With Solid Tumor Harboring an NRG1 Fusion

Solid Tumor, Adult
Samsung Medical Center30 enrolled1 locationNCT06383884
Recruiting
Phase 1Phase 2

Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer

Solid Tumor, AdultOligometastatic Disease
Gustave Roussy, Cancer Campus, Grand Paris58 enrolled2 locationsNCT06439888