Phase 2 Spinal Clinical Trials
51 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 51 trials
Recruiting
Phase 2
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
Spinal Muscular Atrophy (SMA)
argenx60 enrolled17 locationsNCT07287982
Recruiting
Phase 2Phase 3
Tranexamic Acid to Reduce Blood Loss in Spine Surgery
Spinal DeformitySpinal Injuries
Columbia University252 enrolled4 locationsNCT02314988
Recruiting
Phase 2
A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With Spinal Muscular Atrophy
Muscular Atrophy, Spinal
Hoffmann-La Roche10 enrolled13 locationsNCT05808764
Recruiting
Phase 2
Treating Spinal Cord Injury With Early Normobaric Hyperoxia
Traumatic Spinal Cord Injuries
University of Florida12 enrolled1 locationNCT07465302
Recruiting
Phase 2
A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy
Spinal Muscular AtrophySMASpinal Muscular Atrophy Type 3+3 more
Scholar Rock, Inc.52 enrolled25 locationsNCT07047144
Recruiting
Phase 1Phase 2
Psilocybin to Treat Depression in Spinal Cord Injury
Depression - Major Depressive DisorderSpinal Cord InjuryVeteran
James J. Peters Veterans Affairs Medical Center30 enrolled1 locationNCT07251491
Recruiting
Phase 2
Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery
AnesthesiaSpinal FusionNausea and Vomiting, Postoperative
IWK Health Centre100 enrolled1 locationNCT06357234
Recruiting
Phase 2
Risk Adapted Spinal Cord/Cauda Constraint Relaxation for High-risk Patients With Metastatic Epidural Spinal Cord Compression Undergoing Spine Stereotactic Radiosurgery
Spinal CordMetastatic EpiduralSpine Stereotactic
M.D. Anderson Cancer Center60 enrolled1 locationNCT06204315
Recruiting
Phase 2Phase 3
Transcutaneous Spinal Cord Stimulation for Upper Extremity Function
StrokeSpinal Cord Injuries
University of Alberta30 enrolled2 locationsNCT06596369
Recruiting
Phase 1Phase 2
CE-STAND: Cervical Epidural STimulation After Neurologic Damage
Spinal Cord Injury
University of Minnesota36 enrolled1 locationNCT06410001
Recruiting
Phase 1Phase 2
NVG-291 in Spinal Cord Injury Subjects
chronic spinal cord injurySpinal Cord InjuriesSubacute Spinal Cord Injury
NervGen Pharma40 enrolled1 locationNCT05965700
Recruiting
Phase 2
CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury
Urinary IncontinenceSpinal Cord InjurySupra-sacral Spinal Cord Injury
University of Wisconsin, Madison20 enrolled1 locationNCT06840899
Recruiting
Phase 1Phase 2
Study of Safety, Tolerability and Efficacy of GB221 in Infants With Spinal Muscular Atrophy Type 1
Spinal Muscular Atrophy Type I
Gemma Biotherapeutics22 enrolled1 locationNCT07070999
Recruiting
Phase 2
Safety and Efficacy of NMD670 in Ambulatory Adult Patients With Type 3 Spinal Muscular Atrophy
Spinal Muscular Atrophy
NMD Pharma A/S54 enrolled31 locationsNCT05794139
Recruiting
Phase 1Phase 2
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization
neurogenic detrusor overactivitySpinal Cord Injuries
EG 42716 enrolled4 locationsNCT06596291
Recruiting
Phase 2
Phase II Cohort of Spinal Stereotactic Radiotherapy in Patients Using a MR LINAC
Spinal Disease
M.D. Anderson Cancer Center40 enrolled1 locationNCT05709782
Recruiting
Phase 2
Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
StrokeSpinal Cord InjuryAble Bodied
Centre National de la Recherche Scientifique, France45 enrolled2 locationsNCT07334977
Recruiting
Phase 2Phase 3
Epidural Stimulation and Resistance Training After SCI
Spinal Cord Injuries
United States Department of Defense20 enrolled1 locationNCT04782947
Recruiting
Phase 2
Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries
Urinary IncontinenceSpinal Cord Injuries
The University of Texas Medical Branch, Galveston24 enrolled2 locationsNCT04565925
Recruiting
Phase 2Phase 3
IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study
Surgery--ComplicationsIron-deficiencySpinal Fusion+4 more
Columbia University120 enrolled1 locationNCT07217873