Phase 2 Spinal Clinical Trials
52 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 52 trials
Recruiting
Phase 1Phase 2
Study of Safety, Tolerability and Efficacy of GB221 in Infants With Spinal Muscular Atrophy Type 1
Spinal Muscular Atrophy Type I
Gemma Biotherapeutics22 enrolled1 locationNCT07070999
Recruiting
Phase 2
Using Smartphones to Improve Physical Activity Levels of Individuals With Spinal Cord Injury
Spinal Cord Injuries
Temple University196 enrolled1 locationNCT05317832
Recruiting
Phase 2
Study of Olutasidenib and Temozolomide in HGG
Metastatic Brain TumorIDH1 MutationAstrocytoma, Grade IV+16 more
Rigel Pharmaceuticals60 enrolled20 locationsNCT06161974
Recruiting
Phase 1Phase 2
Double Dose 4-AP on Functional Recovery After Spinal Cord Injury
SCI - Spinal Cord Injury
Shirley Ryan AbilityLab27 enrolled1 locationNCT06853015
Recruiting
Phase 2Phase 3
Non-Invasive Neuromodulation for Upper Extremity Function in Spinal Cord Injury: A Crossover Trial
Spinal Cord Injury Cervical
University of Alberta10 enrolled1 locationNCT06903416
Recruiting
Phase 2Phase 3
Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)
Metabolic SyndromeSpinal Cord InjuryTraumatic Spinal Cord Injury+1 more
Northwell Health60 enrolled3 locationsNCT07625332
Recruiting
Phase 2
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
Spinal Muscular Atrophy (SMA)
argenx60 enrolled17 locationsNCT07287982
Recruiting
Phase 2Phase 3
Tranexamic Acid to Reduce Blood Loss in Spine Surgery
Spinal DeformitySpinal Injuries
Columbia University252 enrolled4 locationsNCT02314988
Recruiting
Phase 2
A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With Spinal Muscular Atrophy
Muscular Atrophy, Spinal
Hoffmann-La Roche10 enrolled13 locationsNCT05808764
Recruiting
Phase 2
Treating Spinal Cord Injury With Early Normobaric Hyperoxia
Traumatic Spinal Cord Injuries
University of Florida12 enrolled1 locationNCT07465302
Recruiting
Phase 2
A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy
Spinal Muscular AtrophySMASpinal Muscular Atrophy Type 3+3 more
Scholar Rock, Inc.52 enrolled25 locationsNCT07047144
Recruiting
Phase 1Phase 2
Psilocybin to Treat Depression in Spinal Cord Injury
Depression - Major Depressive DisorderSpinal Cord InjuryVeteran
James J. Peters Veterans Affairs Medical Center30 enrolled1 locationNCT07251491
Recruiting
Phase 2
Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery
AnesthesiaSpinal FusionNausea and Vomiting, Postoperative
IWK Health Centre100 enrolled1 locationNCT06357234
Recruiting
Phase 2
Risk Adapted Spinal Cord/Cauda Constraint Relaxation for High-risk Patients With Metastatic Epidural Spinal Cord Compression Undergoing Spine Stereotactic Radiosurgery
Spinal CordMetastatic EpiduralSpine Stereotactic
M.D. Anderson Cancer Center60 enrolled1 locationNCT06204315
Recruiting
Phase 2Phase 3
Transcutaneous Spinal Cord Stimulation for Upper Extremity Function
StrokeSpinal Cord Injuries
University of Alberta30 enrolled2 locationsNCT06596369
Recruiting
Phase 1Phase 2
CE-STAND: Cervical Epidural STimulation After Neurologic Damage
Spinal Cord Injury
University of Minnesota36 enrolled1 locationNCT06410001
Recruiting
Phase 1Phase 2
NVG-291 in Spinal Cord Injury Subjects
chronic spinal cord injurySpinal Cord InjuriesSubacute Spinal Cord Injury
NervGen Pharma40 enrolled1 locationNCT05965700
Recruiting
Phase 2
CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury
Urinary IncontinenceSpinal Cord InjurySupra-sacral Spinal Cord Injury
University of Wisconsin, Madison20 enrolled1 locationNCT06840899
Recruiting
Phase 2
Safety and Efficacy of NMD670 in Ambulatory Adult Patients With Type 3 Spinal Muscular Atrophy
Spinal Muscular Atrophy
NMD Pharma A/S54 enrolled31 locationsNCT05794139
Recruiting
Phase 1Phase 2
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization
neurogenic detrusor overactivitySpinal Cord Injuries
EG 42716 enrolled4 locationsNCT06596291