Stress Disorder Clinical Trials

333 recruitingLast updated: June 18, 2026

There are 333 actively recruiting stress disorder clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1, Early Phase 1. Top locations include Houston, Texas, United States, Boston, Massachusetts, United States, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Stress Disorder Trials at a Glance

333 actively recruiting trials for stress disorder are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 216 trials, with the heaviest enrollment activity in Houston, Boston, and New York. Lead sponsors running stress disorder studies include VA Office of Research and Development, Yale University, and Karolinska Institutet.

Browse stress disorder trials by phase

Treatments under study

About Stress Disorder Clinical Trials

Looking for clinical trials for Stress Disorder? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Stress Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Stress Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 333 trials

Recruiting
Not Applicable

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

DepressionPregnancy RelatedMedication Adherence+1 more
Boston University Charles River Campus118 enrolled2 locationsNCT05624931
Recruiting
Not Applicable

Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)

PregnancyPosttraumatic Stress Disorder (PTSD)
University of Texas at Austin60 enrolled1 locationNCT07060144
Recruiting
Phase 4

Computational Assessment of GABA Receptor Modulation in PTSD

Stress Disorders, Post-Traumatic
VA Office of Research and Development150 enrolled1 locationNCT06852469
Recruiting
Not Applicable

Transcranial Magnetic Stimulation in Veterans With PTSD

PTSD - Post Traumatic Stress Disorder
White River Junction Veterans Affairs Medical Center20 enrolled1 locationNCT07336251
Recruiting
Not Applicable

Integrated Health Care for PTSD

Posttraumatic Stress Disorder (PTSD)
Veterans Medical Research Foundation300 enrolled5 locationsNCT07220681
Recruiting
Not Applicable

Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Post Traumatic Stress Disorder (PTSD)HIV
Montefiore Medical Center20 enrolled1 locationNCT05929911
Recruiting

Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (PET) and the Radiotracer [18F]PF974

Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Yale University160 enrolled1 locationNCT07488819
Recruiting
Not Applicable

People Bereaved by Violent Death : Negative Event Biases and Temporal Perception

Post Traumatic Stress Disorder
Hôpital le Vinatier61 enrolled1 locationNCT05874362
Recruiting
Phase 3

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

Post Traumatic Stress Disorder
Transcend Therapeutics300 enrolled32 locationsNCT07456696
Recruiting
Phase 2

Mindfulness-based Psilocybin Therapy for PTSD

Depression - Major Depressive DisorderPost Traumatic Stress Disorder
Anthony P King30 enrolled1 locationNCT07104916
Recruiting
Not Applicable

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

Post Traumatic Stress DisorderObsessive-Compulsive DisorderSocial Anxiety Disorder+2 more
Jasper A. Smits600 enrolled2 locationsNCT05467683
Recruiting
Not Applicable

The Efficacy and Safety of Temporal Interference Stimulation in the Treatment of Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder (PTSD)
Shanghai Mental Health Center5 enrolled1 locationNCT07644338
Recruiting
Not Applicable

Manage Emotions to Reduce Aggression (MERA)

Stress Disorders, Post-TraumaticAggressionEmotion Regulation
VA Office of Research and Development204 enrolled2 locationsNCT04793776
Recruiting
Not Applicable

Targeted Plasticity Therapy for PTSD

PTSD - Post Traumatic Stress Disorder
The University of Texas at Dallas20 enrolled3 locationsNCT06266364
Recruiting

Predictability of the Clinical Global Impression Scale (CGI) in Post Immediate in Psychotraumatic Impact

Post Traumatic Stress Disorder
Centre Hospitalier Arras241 enrolled5 locationsNCT05358067
Recruiting
Not Applicable

ERP to Improve Functioning in Veterans With OCD

Obsessive Compulsive Disorder (OCD)Comorbid Post-Traumatic Stress Disorder and OCD
VA Office of Research and Development160 enrolled19 locationsNCT05240924
Recruiting
Not Applicable

Preventive Narrative Exposure Intervention for PTSD in ICU Patients After Cardiopulmonary Bypass Cardiac Surgery

Stress Disorders, Post-TraumaticCardiopulmonary BypassIntensive Care Units
First Affiliated Hospital of Fujian Medical University100 enrolled1 locationNCT07632131
Recruiting
Phase 2

Department of Defense PTSD Adaptive Platform Trial - Master Protocol

Post Traumatic Stress Disorder
Global Coalition for Adaptive Research800 enrolled9 locationsNCT05422612
Recruiting
Not Applicable

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

Post Traumatic Stress Disorder (PTSD)Opioid-use DisorderIntimate Partner Violence (IPV)
Yale University532 enrolled3 locationsNCT07115030
Recruiting
Phase 2Phase 3

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

Post Traumatic Stress DisorderAlcohol Use Disorder
VA Office of Research and Development80 enrolled2 locationsNCT07118839