Mood Disorders Clinical Trials

30 recruiting

Frequently Asked Questions

Common questions about Mood Disorders clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting

Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders

Anxiety DisordersMood Disorders
National Institute of Mental Health (NIMH)390 enrolled1 locationNCT00397111
Recruiting

Psychotropic-Drug-induced QT Prolongation and ECG Monitoring in the Pediatric Population

Eating DisordersPsychotic DisorderMood Disorders in Children and Adolescents+1 more
Meyer Children's Hospital IRCCS100 enrolled6 locationsNCT06870006
Recruiting
Not Applicable

Neurostimulation Versus Therapy for Problems With Emotions

Eating DisordersAnxiety DisordersObsessive-Compulsive Disorder+12 more
Duke University240 enrolled1 locationNCT05712057
Recruiting

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

DepressionHealthy VolunteersAnxiety Disorders+2 more
National Institute of Mental Health (NIMH)16,000 enrolled1 locationNCT00024635
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting

Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device

Anxiety Disorder GeneralizedADHDDepression Disorders+2 more
Gaize50 enrolled1 locationNCT07389473
Recruiting
Not Applicable

Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders

Psychotic DisordersAnxiety DisordersMood Disorders
Maastricht University Medical Center2,500 enrolled9 locationsNCT05656469
Recruiting
Not Applicable

Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression

Depression - Major Depressive DisorderMood DisordersLate Life Depression (LLD)+1 more
Centre for Addiction and Mental Health280 enrolled2 locationsNCT06854367
Recruiting

An Innovative Master Platform for Clinical Trials in Mood Disorders

Depressive DisorderMood DisordersBipolar and Related Disorders
St. Joseph's Healthcare Hamilton900 enrolled9 locationsNCT06408012
Recruiting
Not Applicable

Imagery Rescripting in Primary Care

Mood DisordersMajor Depressive DiorderLow Self-Esteem
University of Amsterdam12 enrolled1 locationNCT07362511
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Not Applicable

Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT

Depression - Major Depressive DisorderOlder Adults (65 Years and Older)Mood Disorders+3 more
KU Leuven82 enrolled1 locationNCT07211750
Recruiting
Not Applicable

Cold and Heat Investigation to Lower Levels of Depression

DepressionMood DisordersHealthy (Controls)
Barry Sandler162 enrolled1 locationNCT06263738
Recruiting
Not Applicable

MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMI

Schizophrenia Spectrum DisordersPsychotic Affective DisordersPsychotic Mood Disorders+2 more
VA Office of Research and Development50 enrolled1 locationNCT06138054
Recruiting
Not Applicable

RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

Anxiety DepressionDepressionAnxiety+3 more
University of Pittsburgh150 enrolled3 locationsNCT05658796
Recruiting
Not Applicable

Mechanisms of Rumination Change in Adolescent Depression

Major Depressive DisorderMood Disorders
Ohio State University183 enrolled3 locationsNCT03859297
Recruiting
Not Applicable

Suicide Specific Rumination in Veterans

DepressionSuicideMood Disorders
VA Office of Research and Development15 enrolled1 locationNCT06481033
Recruiting
Not Applicable

Feasibility and Acceptability of an E-learning Dialectical Behavior Therapy Skills Course

DepressionStressAnxiety+2 more
University of Windsor40 enrolled1 locationNCT07088939
Recruiting

Clinical Validation of Samsung Smartwatch

Mental Health IssueMajor Depressive DisorderMood Disorders
Massachusetts General Hospital220 enrolled1 locationNCT05767593
Recruiting
Not Applicable

Neuro-computational Study of Thymic Fluctuations in Mood Disorders

DepressionBipolar DisorderMood Disorders+1 more
Centre Hospitalier St Anne588 enrolled2 locationsNCT07033923