Phase 1 Stress Disorder Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1Phase 2

Mitigating PTSD-CUD After Sexual Assault

Cannabis Use DisorderPosttraumatic Stress Disorder
University of Nevada, Las Vegas68 enrolled6 locationsNCT05989841
Recruiting
Phase 1

Inflammatory Challenge and Fear

Posttraumatic Stress Disorder (PTSD)
University of California, San Francisco288 enrolled1 locationNCT06630884
Recruiting
Phase 1

Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study

Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance10 enrolled1 locationNCT06335407
Recruiting
Phase 1

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

Posttraumatic Stress Disorder
Johns Hopkins University40 enrolled1 locationNCT06989957
Not Yet Recruiting
Phase 1

Testing the Safety and Effects of the Psychedelic Psilocin on Wellbeing and Anxiety in People with Ongoing Physical and Mental Health Conditions

Chronic Fatigue SyndromeAnorexia NervosaFibromyalgia+6 more
Tryptamine Therapeutics66 enrolled1 locationACTRN12625000949482
Recruiting
Phase 1

Alexithymia Intervention for Suicide

SchizophreniaPost Traumatic Stress DisorderSuicide+2 more
VA Office of Research and Development40 enrolled1 locationNCT05724953
Recruiting
Phase 1

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

Post Traumatic Stress DisorderDepressive Disorder, Major
Yale University50 enrolled1 locationNCT05915013
Completed
Phase 1

Treatment of Anxiety and Depression in Head and Neck Cancer Patients

Anxiety (including Acute Stress Disorder and Posttraumatic Stress Disorder) in Head and Neck Cancer.Depression in Head and Neck Cancer.
Dr Maria Kangas, Macquarie University Sydney Australia160 enrolled1 locationACTRN12607000219482
Not Yet Recruiting
Phase 1

Vietnam Veterans - Real Partners in Health: Does self-management support improve your health?

Alcohol-related disorders in Vietnam VeteransMajor Depression in Vietnam VeteransPost Traumatic Stress Disorder in Vietnam Veterans
Department of Veteran Affairs200 enrolled1 locationACTRN12606000422527