Systolic Dysfunction Clinical Trials

2 recruiting

Systolic Dysfunction Trials at a Glance

14 actively recruiting trials for systolic dysfunction are listed on ClinicalTrialsFinder across 6 cities in 39 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in São Paulo, New York, and Belgrade. Lead sponsors running systolic dysfunction studies include Berlin Heals GmbH, Cairo University, and Bayer.

Browse systolic dysfunction trials by phase

Treatments under study

About Systolic Dysfunction Clinical Trials

Looking for clinical trials for Systolic Dysfunction? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Systolic Dysfunction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Systolic Dysfunction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Phase 2Phase 3

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled105 locationsNCT05714085
Recruiting
Phase 3

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Not Applicable

Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular Lead

Non-ischemic CardiomyopathyLeft Ventricular (LV) Systolic DysfunctionIdiopathic Cardiomyopathy
Berlin Heals GmbH22 enrolled4 locationsNCT06920030
Recruiting
Not Applicable

Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass

Coronary Artery Disease (CAD)FentanylLeft Ventricular (LV) Systolic Dysfunction+4 more
Cairo University40 enrolled1 locationNCT07248202
Recruiting

Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study

Left Ventricular Systolic Dysfunction
Mayo Clinic30 enrolled1 locationNCT06770062
Recruiting
Not Applicable

AI-Enabled Electrocardiogram-Guided Guideline-Directed Medical Therapy on Incident Left Ventricular Dysfunction: A Target Trial Emulation Study

Left Ventricular (LV) Systolic Dysfunction
Tri-Service General Hospital5,000 enrolled1 locationNCT07355023
Recruiting

Fibrosis in Chronic and Delayed Myocardial Infarction

Carcinoid SyndromeAortic StenosisChemotherapy Induced Systolic Dysfunction
University of Edinburgh180 enrolled1 locationNCT05756608
Recruiting
Not Applicable

Hybrid Ablation of Atrial Fibrillation in Heart Failure

Heart FailureAtrial FibrillationAtrial Arrhythmia+3 more
St. George's Hospital, London120 enrolled7 locationsNCT05411614
Recruiting
Phase 4

Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure

Iron-deficiencyChronic Heart FailureLeft Ventricular Systolic Dysfunction
Raffaele De Caterina60 enrolled1 locationNCT06270498
Recruiting

STICH3C Cardiac Magnetic Resonance Observational Study

Multivessel Coronary Artery DiseaseIschemic Left Ventricle Systolic Dysfunction
Weill Medical College of Cornell University200 enrolled9 locationsNCT07133984
Recruiting
Not Applicable

Cardiac Contractility Modulation in Chagas Heart Disease

Heart FailureSystolic DysfunctionChagas Cardiomyopathy+2 more
InCor Heart Institute60 enrolled1 locationNCT05519046
Recruiting

AI-based Prediction of Cardiac Function Using Echocardiography and Body Composition Data (ECHO-FIT Study)

Heart FailureArtificial Intelligence (AI)Body Composition Measurement+1 more
Yonsei University2,000 enrolled1 locationNCT06811519
Recruiting
Phase 1Phase 2

Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES

Diastolic DysfunctionSystolic DysfunctionDiastolic Heart Failure
Texas Tech University Health Sciences Center200 enrolled1 locationNCT05408559
Recruiting

Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography

Chronic Kidney DiseasesLeft Ventricular Systolic Dysfunction
Fifth Affiliated Hospital, Sun Yat-Sen University500 enrolled1 locationNCT06221891