T2DM Clinical Trials

6 recruiting

Frequently Asked Questions

Common questions about T2DM clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 83 trials

Recruiting
Phase 1

A Study of REGEND003 on Patients With Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD)

Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD)
Regend Therapeutics15 enrolled1 locationNCT07275788
Recruiting
Not Applicable

Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)Type 2 Diabetes
Stanford University30 enrolled1 locationNCT06836479
Recruiting
Not Applicable

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

Type 2 Diabetes Mellitus (T2DM)Chronic Kidney Disease(CKD)Type 2 DM
Duke University420 enrolled6 locationsNCT06906640
Recruiting
Not Applicable

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

Type 2 Diabetes Mellitus (T2DM)Chronic Kidney Disease(CKD)Type 2 DM
Duke University750 enrolled6 locationsNCT06906627
Recruiting

Investigation of Motor Imagery Ability, Body Awareness and Cognitive Functions in Type 2 Diabetes Mellitus

Cognitive FunctionType 2 Diabetes Mellitus (T2DM)Motor İmagery Ability
Kutahya Health Sciences University100 enrolled1 locationNCT06588894
Recruiting
Phase 2

A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals40 enrolled1 locationNCT07465224
Recruiting
Phase 3

A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome

Type 2 Diabetes (T2DM)LipidemiaMetabolic Syndrome (MetS)
NewAmsterdam Pharma300 enrolled20 locationsNCT07219602
Recruiting
Not Applicable

Achieving Routine Intervention and Screening for Emotional Health

Type 2 Diabetes Mellitus (T2DM)Diabetes Distress
University of Chicago1,250 enrolled1 locationNCT06887049
Recruiting
Not Applicable

Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge

Type 1 Diabetes Mellitus (T1DM)Type 2 Diabetes Mellitus (T2DM)Hyperglycemia
Vanderbilt University Medical Center60 enrolled1 locationNCT06852950
Recruiting
Phase 4

Glycemic Variability of Combination Therapies in T2DM

Type 2 Diabetes Mellitus (T2DM)
JW Pharmaceutical178 enrolled1 locationNCT07442006
Recruiting

The Establishment of Hong Kong Diabetes Steatotic Liver Disease Register

Metabolic Dysfunction-Associated Steatotic Liver DiseaseType 2 Diabetes (T2DM)
Chinese University of Hong Kong1,000 enrolled1 locationNCT07437157
Recruiting
Not Applicable

Human Immunodeficiency Virus (HIV) Food Insecurities

Type 2 Diabetes Mellitus (T2DM)PrediabetesHIV+2 more
Wake Forest University Health Sciences200 enrolled1 locationNCT04943861
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled2 locationsNCT06845202
Recruiting
Not Applicable

Para-Probiotic Oral Care in Periodontal Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)Periodontitis
University of Pavia40 enrolled1 locationNCT07069166
Recruiting
Not Applicable

Side-to-Side Duodeno-ileostomy Versus Semaglutide in Adults With Obesity and Type 2 Diabetes

Obesity, OverweightType 2 Diabetes (T2DM)Obesity (Disorder)
GT Metabolic Solutions, Inc.20 enrolled1 locationNCT07317115
Recruiting
Not Applicable

Glucagon Resistance in Patients With MASLD and T2DM

Type 2 Diabetes (T2DM)Metabolic Associated Fatty Liver Disease
University of Aarhus24 enrolled1 locationNCT07246421
Recruiting

Psychological Well-Being, Depression, and Health-Related Quality of Life in Adults With Type 2 Diabetes: A Cross-Sectional Study

Spiritual Well-beingDepressive SymptomsType 2 Diabetes Mellitus (T2DM)+2 more
National Taiwan University Hospital500 enrolled1 locationNCT07241325
Recruiting
Not Applicable

Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal

HypertensionType 2 Diabetes Mellitus (T2DM)Tobacco Smoking
Johns Hopkins Bloomberg School of Public Health2,070 enrolled1 locationNCT06740708
Recruiting

Nutritional Management of the Patient With Type 2 Diabetes at Nutritional Risk or With Malnutrition in Clinical Practice

Type 2 Diabetes Mellitus (T2DM)MalnutritionMalnourishment+1 more
Outcomes'10334 enrolled12 locationsNCT07252765
Recruiting
Not Applicable

Transition to Hospital Discharge in Insulinized Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)Continuous Glucose MonitoringCGM+2 more
Instituto de Investigacion Sanitaria La Fe80 enrolled1 locationNCT07061301