Phase 2 Thoracic Clinical Trials

16 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 116 of 16 trials

Recruiting
Phase 1Phase 2

A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma
MediLink Therapeutics (Suzhou) Co., Ltd.118 enrolled22 locationsNCT07407933
Recruiting
Phase 1Phase 2

HEART: Pilot Randomized Controlled Trial

Thoracic Aortic Aneurysm
Mayo Clinic50 enrolled1 locationNCT07483177
Recruiting
Phase 1Phase 2

Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS)

Head and Neck CancerThoracic CancerTesticular Cancer+1 more
University of Arizona25 enrolled1 locationNCT07407582
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Lung CancerNSCLCThoracic Cancer+5 more
Tango Therapeutics, Inc.183 enrolled18 locationsNCT06922591
Recruiting
Phase 2

Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage SCLC Patients

Limited Stage Small Cell Lung CancerThoracic NeoplasmsRespiratory Tract Neoplasms+1 more
Fundación GECP37 enrolled20 locationsNCT07242547
Recruiting
Phase 2

HEARTS Trial for Thoracic Cancers

Non-Small Cell Lung Cancer (Stage III)Esophageal Cancer Stage I-IIIEsophagogastric Cancer Stage I-III+2 more
University of Wisconsin, Madison60 enrolled1 locationNCT07132918
Recruiting
Phase 2Phase 3

High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

Lung Cancer (NSCLC)AnalgeticVideo Assisted Thoracic Surgery (VATS)+1 more
Rigshospitalet, Denmark80 enrolled1 locationNCT07213375
Recruiting
Phase 2

Perioperative Cadonilimab Combined With Neoadjuvant Chemotherapy in Resectable Esophageal Squamous Cell Carcinoma (ESCC)

Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
Akeso90 enrolled1 locationNCT07263919
Recruiting
Phase 2

Clinical Study of Thiopegfilgrastim for Preventing Bone Marrow Suppression in Thoracic Tumor Chemoradiotherapy

Thoracic NeoplasmsChemoradiotherapyMyelosuppression
Affiliated Hospital of Nantong University30 enrolled1 locationNCT07205536
Recruiting
Phase 2

Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer

Lung NeoplasmsThoracic NeoplasmsLung Diseases+1 more
Shanghai Pulmonary Hospital, Shanghai, China15 enrolled1 locationNCT06758700
Recruiting
Phase 2

PALACE: Cemiplimab Trial According to ctDNA Levels

Non-small Cell Lung Cancer MetastaticThoracic NeoplasmsStage IV Non-Small Cell Lung Cancer+3 more
Fundación GECP63 enrolled20 locationsNCT06917573
Recruiting
Phase 1Phase 2

Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial

Critical IllnessThoracic SurgeryPost-operative Complication
Wandercraft5 enrolled1 locationNCT07220733
Recruiting
Phase 2

Radiotherapy Plus Anlotinib in LA-NSCLC Intolerable to cCRT

SafetyLocally Advanced Non-Small Cell Lung CancerThoracic Radiotherapy
JIANYANG WANG44 enrolled1 locationNCT07037680
Recruiting
Phase 2Phase 3

Preoperative Paravertebral Block in Cancer Surgery of the Lung

Thoracic NeoplasmChronic Pain Post-ProceduralAcute Post-thoracotomy Pain+1 more
Guy's and St Thomas' NHS Foundation Trust100 enrolled1 locationNCT04209868
Recruiting
Phase 2

A Phase Ⅱ Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLC

Lung NeoplasmsNeoplasmsNeoplasms by Site+7 more
Nanfang Hospital, Southern Medical University62 enrolled1 locationNCT06177925
Not Yet Recruiting
Phase 2

Sodium-Glucose Co-Transporter 2 inhibition prior to cardiac surgery and postoperative atrial fibrillation: a pilot randomised controlled trial

Cardiothoracic surgery
Flinders University16 enrolled1 locationACTRN12621000684820