Phase 2 Thyroid Clinical Trials

58 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 58 trials

Recruiting
Phase 1Phase 2

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Colorectal, CancerColorectal CarcinomaNon-small Cell Lung Cancer+29 more
Institut de Recherches Internationales Servier554 enrolled27 locationsNCT05786924
Recruiting
Phase 2

Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer

Thyroid Cancer
Thomas Hope62 enrolled1 locationNCT06961084
Recruiting
Phase 1Phase 2

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

Thyroid Eye Disease
Amgen88 enrolled38 locationsNCT06401044
Recruiting
Phase 2

The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer

Metastic Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)54 enrolled1 locationNCT04927416
Recruiting
Phase 2

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled1 locationNCT03841617
Recruiting
Phase 2

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

Neoadjuvant TreatmentThyroid Cancer
M.D. Anderson Cancer Center45 enrolled2 locationsNCT06959511
Recruiting
Phase 2Phase 3

Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors

Primary HyperparathyroidismParathyroid CancerMultiple Endocrine Neoplasias+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)193 enrolled1 locationNCT07444723
Recruiting
Phase 2Phase 3

Trop2-targeted immunoPET Imaging of Solid Tumors

Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 2

An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease

Thyroid Eye Disease
Amgen30 enrolled1 locationNCT07438405
Recruiting
Phase 1Phase 2

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

Cervical CancerMelanomaNon-small Cell Lung Cancer+8 more
University of Arizona30 enrolled2 locationsNCT06814496
Recruiting
Phase 2

XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer

Stage III Differentiated Thyroid Gland Carcinoma AJCC v8Refractory Differentiated Thyroid Gland CarcinomaLocally Advanced Differentiated Thyroid Gland Carcinoma+18 more
Northwestern University33 enrolled2 locationsNCT06959641
Recruiting
Phase 2

A Randomized Control Trial for Patient Reported Outcomes and Safety in Outpatient Thyroid Lobectomy

Thyroid Lobectomy
M.D. Anderson Cancer Center224 enrolled1 locationNCT06085625
Recruiting
Phase 2

A Cohort Study on the Safety and Efficacy of XH-02 in Treating Hypoparathyroidism

Hypoparathyroidism
Peking Union Medical College Hospital60 enrolled1 locationNCT07540286
Recruiting
Phase 1Phase 2

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

Breast CancerEsophageal CancerPancreatic Cancer+13 more
ModeX Therapeutics, An OPKO Health Company285 enrolled6 locationsNCT06239194
Recruiting
Phase 2

Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye Disease

Graves OrbitopathyGraves OphthalmopathyThyroid Eye Disease (TED)
The First Affiliated Hospital of Xiamen University8 enrolled1 locationNCT07547930
Recruiting
Phase 2

Pembrolizumab in High-risk Thyroid Cancer

Differentiated Thyroid Cancer
Istituti Clinici Scientifici Maugeri SpA25 enrolled1 locationNCT05852223
Recruiting
Phase 2

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

CancerPediatric CancerDifferentiated Thyroid Cancer+1 more
Children's Hospital of Philadelphia13 enrolled4 locationsNCT06458036
Recruiting
Phase 2

Agnostic Therapy in Rare Solid Tumors

Cancer of Unknown PrimarySoft Tissue SarcomaCholangiocarcinoma+38 more
Instituto do Cancer do Estado de São Paulo28 enrolled8 locationsNCT06638931
Recruiting
Phase 1Phase 2

Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult Hypoparathyroidism

Hypoparathyroidism
Peking Union Medical College Hospital15 enrolled1 locationNCT07530705
Recruiting
Phase 2

A Study of Avutometinib and Defactinib in People With Thyroid Cancer

Thyroid Cancer
Memorial Sloan Kettering Cancer Center30 enrolled7 locationsNCT06007924