Thyroid Clinical Trials

405 recruitingLast updated: June 20, 2026

There are 405 actively recruiting thyroid clinical trials across 46 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4, Early Phase 1. Top locations include Houston, Texas, United States, Shanghai, Shanghai Municipality, China, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Thyroid Trials at a Glance

405 actively recruiting trials for thyroid are listed on ClinicalTrialsFinder across 6 cities in 46 countries. The largest study group is Not Applicable with 108 trials, with the heaviest enrollment activity in Houston, Shanghai, and New York. Lead sponsors running thyroid studies include M.D. Anderson Cancer Center, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, and Fudan University.

Treatments under study

About Thyroid Clinical Trials

Looking for clinical trials for Thyroid? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Thyroid trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Thyroid clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 405 trials

Recruiting

Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer

Non-Medullary Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)500 enrolled1 locationNCT01109420
Recruiting

Studies on Tumors of the Thyroid

Thyroid CancerPapillary Thyroid CancerFollicular Thyroid Cancer+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,500 enrolled1 locationNCT00001160
Recruiting
Phase 1

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center44 enrolled1 locationNCT03093909
Recruiting
Phase 1Phase 2

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Colorectal, CancerColorectal CarcinomaNon-small Cell Lung Cancer+29 more
Institut de Recherches Internationales Servier554 enrolled27 locationsNCT05786924
Recruiting
Phase 2

Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer

Thyroid Cancer
Thomas Hope62 enrolled1 locationNCT06961084
Recruiting
Not Applicable

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

MelanomaBreast Cancer, NOSCNS Primary Tumor, NOS+9 more
Eastern Cooperative Oncology Group400 enrolled347 locationsNCT05108298
Recruiting
Phase 3

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Refractory Differentiated Thyroid Gland Carcinoma
ECOG-ACRIN Cancer Research Group264 enrolled301 locationsNCT06475989
Recruiting

Environmental Factors and Thyroid Cancer

Thyroid Cancer
Icahn School of Medicine at Mount Sinai500 enrolled1 locationNCT05172921
Recruiting

Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

Endocrine TumorsNeuroblastomaThyroid Neoplasms+2 more
National Cancer Institute (NCI)2,415 enrolled1 locationNCT01005654
Recruiting
Phase 4

The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response

surgical stress responseThyroid CancerThyroid and Parathyroid Surgery+1 more
University Hospital Dubrava48 enrolled1 locationNCT07600580
Recruiting

Precision Medicine Approaches to Renal Osteodystrophy

Chronic Kidney DiseasesCkd-MbdSecondary Hyperparathyroidism+2 more
Thomas Nickolas40 enrolled1 locationNCT05880914
Recruiting
Phase 1Phase 2

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

Thyroid Eye Disease
Amgen88 enrolled38 locationsNCT06401044
Recruiting
Not Applicable

Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism

Hyperparathyroidism, Primary
University of Pennsylvania76 enrolled1 locationNCT06562881
Recruiting
Not Applicable

Hereditary Risk Factors for Thyroid Cancer

Thyroid Cancer
Dana-Farber Cancer Institute250 enrolled1 locationNCT02747888
Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

MelanomaNon-small Cell Lung CancerThyroid Cancer+10 more
Pfizer124 enrolled82 locationsNCT05538130
Recruiting

Natural History Study of Children and Adults With Medullary Thyroid Cancer

Medullary Thyroid Cancer
National Cancer Institute (NCI)259 enrolled1 locationNCT01660984
Recruiting
Phase 2

The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer

Metastic Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)54 enrolled1 locationNCT04927416
Recruiting
Phase 2

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled1 locationNCT03841617
Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

MelanomaNon-small Cell Lung CancerThyroid Cancer+2 more
Pfizer267 enrolled40 locationsNCT05355701
Recruiting
Not Applicable

Development and Application of an AI Chatbot for Perioperative Health Education in Thyroid Cancer Patients

Thyroid Cancer
Tianjin Medical University Cancer Institute and Hospital150 enrolled1 locationNCT07634978