Phase 1 Toxicity Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1Phase 2
The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study
ToxicityRadiation Toxicity
UNC Lineberger Comprehensive Cancer Center122 enrolled1 locationNCT04700527
Recruiting
Phase 1Phase 2
Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction
Anthracycline Related Cardiotoxicity in Breast Cancer
Texas Tech University Health Sciences Center70 enrolled1 locationNCT03934905
Recruiting
Phase 1Phase 2
Hypofraction Radiotherapy for Locally Advanced Non-small Cell Lung Cancer
Non-small Cell Lung CancerToxicity Due to Radiotherapy
Anhui Provincial Hospital36 enrolled1 locationNCT05269485
Recruiting
Phase 1
OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.
Pleural CarcinomatosisQuality of LifeChemotherapy Effect+4 more
Odense University Hospital20 enrolled1 locationNCT06421610
Completed
Phase 1
A study to evaluate the safety and pharmacokinetics of DB-020 when administered to healthy participants
Ototoxicity
Decibel Therapeutics Australia Pty Ltd40 enrolled1 locationACTRN12618001710213
Completed
Phase 1
Ibudilast for the prevention of nerve symptoms caused by oxalipatin chemotherapy, in patients with metastatic gastrointestinal cancer
Metastatic gastrointestinal cancerAcute neurotoxicity
Concord Cancer Centre20 enrolled1 locationACTRN12618000232235
Completed
Phase 1
Investigating computed tomography ventilation as a functional imaging modality for lung cancer radiotherapy
Radiotherapy toxicity in lung cancer radiotherapy
University of Sydney30 enrolled1 locationACTRN12612000775819