Phase 2 Toxicity Clinical Trials
27 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 27 trials
Recruiting
Phase 1Phase 2
The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study
ToxicityRadiation Toxicity
UNC Lineberger Comprehensive Cancer Center122 enrolled1 locationNCT04700527
Recruiting
Phase 2
Rivastigmine for Antimuscarinic Delirium
Anticholinergic Toxicity
Washington University School of Medicine42 enrolled1 locationNCT06382649
Recruiting
Phase 2
A Study of Blood Pressure Control During Cancer Treatment
Breast CancerCardiotoxicity
Memorial Sloan Kettering Cancer Center130 enrolled7 locationsNCT06023576
Recruiting
Phase 2
Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin
Ototoxicity, Drug-Induced
Kevin Winthrop105 enrolled7 locationsNCT05730283
Recruiting
Phase 2
Alpha-Lipoic Acid in Mitigating Cisplatin-Induced Nephrotoxicity
NephrotoxicityCisplatin Nephrotoxicity
Minia University50 enrolled1 locationNCT07564479
Recruiting
Phase 2
Rivastigmine to Prevent Recurrence of Antimuscarinic Delirium
Anticholinergic Toxicity
Washington University School of Medicine42 enrolled1 locationNCT06399679
Recruiting
Phase 2
Protecting the Kidney's Proximal Tubules From Platinum-Based Chemotherapy Toxicity
Solid TumorsCisplatin Nephrotoxicity
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran46 enrolled1 locationNCT07018622
Recruiting
Phase 2
Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled Trial
Sensorineural Hearing LossOtotoxicityOtotoxicity, Drug-Induced+1 more
Siriraj Hospital40 enrolled1 locationNCT07364747
Recruiting
Phase 2
Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients
Breast CancerHeart FailureAnthracycline-induced Cardiac Toxicity+2 more
University Medical Centre Ljubljana100 enrolled1 locationNCT07245069
Recruiting
Phase 2
Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer or Pulmonary Oligometastases
Non-small Cell Lung CancerToxicityAdaptive Radiotherapy+2 more
Sun Yat-sen University130 enrolled1 locationNCT06542159
Recruiting
Phase 2
Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted
Early Stage Breast CancerCardiac Toxicity
Rutgers, The State University of New Jersey60 enrolled10 locationsNCT05559164
Recruiting
Phase 2
Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab
NeoplasmsNeoplasms by SiteUrinary Bladder Neoplasm+8 more
The Netherlands Cancer Institute90 enrolled9 locationsNCT06237920
Recruiting
Phase 2
Clinical Study to Evaluate The Cardioprotective Effect of Pentoxifylline Against Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients
Breast CancerDoxorubicin Induced Cardiotoxicity
Tanta University46 enrolled1 locationNCT07137793
Recruiting
Phase 2
L-Carnitine Protective Effect in Nephrotoxicity
Nephrotoxicity
Tanta University46 enrolled1 locationNCT07108777
Recruiting
Phase 2
The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor
Radiation ToxicityProton RadiotherapyThymus Epithelial Tumor
Jian Chen55 enrolled1 locationNCT06311968
Recruiting
Phase 1Phase 2
Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction
Anthracycline Related Cardiotoxicity in Breast Cancer
Texas Tech University Health Sciences Center70 enrolled1 locationNCT03934905
Recruiting
Phase 2
Treatment of Radiation and Cisplatin Induced Toxicities with Tempol
NephrotoxicityMucositisOtotoxicity
Matrix Biomed, Inc.120 enrolled9 locationsNCT03480971
Recruiting
Phase 1Phase 2
Hypofraction Radiotherapy for Locally Advanced Non-small Cell Lung Cancer
Non-small Cell Lung CancerToxicity Due to Radiotherapy
Anhui Provincial Hospital36 enrolled1 locationNCT05269485
Recruiting
Phase 2
Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis
Esophageal CancerRadiation ToxicityEsophagitis
First Affiliated Hospital of Chengdu Medical College120 enrolled1 locationNCT06392971
Recruiting
Phase 2
Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients
Breast CancerHeart FailureMetastatic Breast Cancer+2 more
University Hospital, Akershus60 enrolled1 locationNCT05732051