Phase 2 Toxicity Clinical Trials
25 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 25 trials
Recruiting
Phase 2
Rivastigmine to Prevent Recurrence of Antimuscarinic Delirium
Anticholinergic Toxicity
Washington University School of Medicine42 enrolled1 locationNCT06399679
Recruiting
Phase 2
Protecting the Kidney's Proximal Tubules From Platinum-Based Chemotherapy Toxicity
Solid TumorsCisplatin Nephrotoxicity
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran46 enrolled1 locationNCT07018622
Recruiting
Phase 2
Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin
Ototoxicity, Drug-Induced
Kevin Winthrop105 enrolled5 locationsNCT05730283
Recruiting
Phase 2
Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled Trial
Sensorineural Hearing LossOtotoxicityOtotoxicity, Drug-Induced+1 more
Siriraj Hospital40 enrolled1 locationNCT07364747
Recruiting
Phase 2
A Study of Blood Pressure Control During Cancer Treatment
Breast CancerCardiotoxicity
Memorial Sloan Kettering Cancer Center130 enrolled7 locationsNCT06023576
Recruiting
Phase 1Phase 2
The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study
ToxicityRadiation Toxicity
UNC Lineberger Comprehensive Cancer Center122 enrolled1 locationNCT04700527
Recruiting
Phase 2
Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients
Breast CancerHeart FailureAnthracycline-induced Cardiac Toxicity+2 more
University Medical Centre Ljubljana100 enrolled1 locationNCT07245069
Recruiting
Phase 2
Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted
Cardiac Toxicity
Rutgers, The State University of New Jersey60 enrolled10 locationsNCT05559164
Recruiting
Phase 2
Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer or Pulmonary Oligometastases
Non-small Cell Lung CancerToxicityAdaptive Radiotherapy+2 more
Sun Yat-sen University130 enrolled1 locationNCT06542159
Recruiting
Phase 2
Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab
NeoplasmsNeoplasms by SiteUrinary Bladder Neoplasm+8 more
The Netherlands Cancer Institute90 enrolled9 locationsNCT06237920
Recruiting
Phase 2
Clinical Study to Evaluate The Cardioprotective Effect of Pentoxifylline Against Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients
Breast CancerDoxorubicin Induced Cardiotoxicity
Tanta University46 enrolled1 locationNCT07137793
Recruiting
Phase 2
L-Carnitine Protective Effect in Nephrotoxicity
Nephrotoxicity
Tanta University46 enrolled1 locationNCT07108777
Recruiting
Phase 2
The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor
Radiation ToxicityProton RadiotherapyThymus Epithelial Tumor
Jian Chen55 enrolled1 locationNCT06311968
Recruiting
Phase 2
Treatment of Radiation and Cisplatin Induced Toxicities with Tempol
NephrotoxicityMucositisOtotoxicity
Matrix Biomed, Inc.120 enrolled9 locationsNCT03480971
Recruiting
Phase 1Phase 2
Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction
Anthracycline Related Cardiotoxicity in Breast Cancer
Texas Tech University Health Sciences Center70 enrolled1 locationNCT03934905
Recruiting
Phase 1Phase 2
Hypofraction Radiotherapy for Locally Advanced Non-small Cell Lung Cancer
Non-small Cell Lung CancerToxicity Due to Radiotherapy
Anhui Provincial Hospital36 enrolled1 locationNCT05269485
Recruiting
Phase 2
Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis
Esophageal CancerRadiation ToxicityEsophagitis
First Affiliated Hospital of Chengdu Medical College120 enrolled1 locationNCT06392971
Recruiting
Phase 2
Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients
Breast CancerHeart FailureMetastatic Breast Cancer+2 more
University Hospital, Akershus60 enrolled1 locationNCT05732051
Not Yet Recruiting
Phase 2
Phase 1b trial to investigate the prevention of hearing loss in cancer patients receiving cisplatin chemotherapy
Hearing loss (ototoxicity from cisplatin medication)
Decibel Therapeutics Australia Pty Ltd70 enrolled5 locationsACTRN12620000182998
Not Yet Recruiting
Phase 2
LANTERN - LAser Nerve ThERapy for chemotherapy Neurotoxicity
neurotoxicity
Concord Cancer Centre45 enrolled1 locationACTRN12619001672145