Phase 3 Toxicity Clinical Trials

10 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 110 of 10 trials

Recruiting
Phase 3

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817
Recruiting
Phase 3

Empagliflozin in the Prevention of Cardiotoxicity in Cancer Patients Undergoing Chemotherapy Based on Anthracyclines

Cardiotoxicity
Maria Sklodowska-Curie National Research Institute of Oncology220 enrolled2 locationsNCT05271162
Recruiting
Phase 3

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Recurrent Breast CarcinomaStage IV Breast Cancer AJCC v6 and v7Cardiotoxicity+2 more
SWOG Cancer Research Network491 enrolled590 locationsNCT03418961
Recruiting
Phase 3

Cardioprotection on Chemotherapy-Induced Cardiotoxicity

Cardiotoxicity
Ain Shams University30 enrolled2 locationsNCT06853951
Recruiting
Phase 3

Implementing Geriatric Assessment for Dose Optimization of Cyclin-dependent Kinase (CDK) 4/6-inhibitors in Older Breast Cancer Patients

Metastatic Breast CancerAdvanced Breast CancerQuality of Life+2 more
Region Örebro County495 enrolled12 locationsNCT06044623
Recruiting
Phase 3

Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC

Hepatocellular CarcinomaChemotherapy EffectChemotherapeutic Toxicity
Sun Yat-sen University540 enrolled1 locationNCT06041477
Recruiting
Phase 3

The Use of Shengmai San to Prevent Anthracycline Sequential Trastuzumab Therapy Related Cardiac Toxicity

Cardiotoxicity Induced by Drug Therapy for Breast Cancer
Zhejiang Cancer Hospital276 enrolled1 locationNCT06214195
Recruiting
Phase 3

Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis

Beta Blocker Toxicity
Sherief Abd-Elsalam50 enrolled1 locationNCT04704947
Recruiting
Phase 3

A comparison of two routinely used skin treatments for women with breast cancer undergoing radiation therapy

Acute radiation therapy (RT) skin toxicity and managementBreast Cancer
Western Sydney Local Health District60 enrolled3 locationsACTRN12619000753156
Not Yet Recruiting
Phase 3

ESPRIT TOXIL-2 UNSW PSO 6361

Interleukin-2 therapyrlL-2 toxicityHIV
University of New South Wales, Sydney, Australia.168 enrolled1 locationACTRN12605000407695