Transplant Failure Clinical Trials

23 recruitingLast updated: May 13, 2026

There are 23 actively recruiting transplant failure clinical trials across 14 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4. Top locations include Los Angeles, California, United States, San Francisco, California, United States, Lyon, France. Updated daily from ClinicalTrials.gov.


Transplant Failure Trials at a Glance

23 actively recruiting trials for transplant failure are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Los Angeles, San Francisco, and Lyon. Lead sponsors running transplant failure studies include Oslo University Hospital, Duke University, and Columbia University.

Browse transplant failure trials by phase

Treatments under study

About Transplant Failure Clinical Trials

Looking for clinical trials for Transplant Failure? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Transplant Failure trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Transplant Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting
Phase 4

Allograft Dysfunction in Heart Transplant

Heart Transplant Failure and Rejection
Paul Kim376 enrolled1 locationNCT03102125
Recruiting

Endothelial Glycocalyx Damage in Brain Death Organ Donors

Brain Damage Due to HypoxiaOrgan DonorsOrgan Transplant Failure or Rejection
University Hospital Hradec Kralove100 enrolled1 locationNCT05609123
Recruiting
Phase 2

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

Corneal Transplant Failure
Massachusetts Eye and Ear Infirmary96 enrolled12 locationsNCT06753916
Recruiting
Phase 3

A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients

Kidney Transplant Failure and RejectionBK ViremiaKidney Transplant Infection
The University of Queensland280 enrolled12 locationsNCT05325008
Recruiting
Phase 2

Pilot Study: Interest of Belatacept as a Non-nephrotoxic Immunosuppressive Treatment in Cardiac Transplant Patients at Risk of Chronic Renal Failure (BELACOEUR)

Heart Transplant Failure
Nantes University Hospital25 enrolled4 locationsNCT04180085
Recruiting
Phase 1

Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants

Chronic Kidney DiseasesEnd-stage Kidney DiseaseKidney Transplant Failure and Rejection+1 more
University of California, Los Angeles10 enrolled1 locationNCT05525507
Recruiting

The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study

Corneal endothelial cell lossCorneal Transplant Failure
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia135 enrolled12 locationsNCT05847387
Recruiting
Phase 2Phase 3

Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant

Heart Transplant InfectionCMV ViremiaHeart Transplant Failure and Rejection
Columbia University150 enrolled2 locationsNCT07079735
Recruiting

Liquid biopsiEs fOr luNg AllogRaft Damage classificatiOn - LEONARDO

Lung Transplant Failure and RejectionLung Transplant Infection
Jesper Magnusson146 enrolled1 locationNCT06679257
Recruiting

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Lung Transplant; ComplicationsLung Transplant; Infection or InflammationLung Transplant Rejection+1 more
Duke University2,600 enrolled17 locationsNCT06399302
Recruiting
Phase 1

Levothyroxine Supplementation for Heart Transplant Recipients

Heart Transplant FailureHeart Transplant Infection
University of California, San Francisco97 enrolled1 locationNCT06428097
Recruiting
Phase 4

Can Dapagliflozin Preserve Structure and Function in Transplanted Kidneys?

Kidney Transplant; ComplicationsRenal FailureKidney Transplant Failure
Oslo University Hospital330 enrolled1 locationNCT05788276
Recruiting
Phase 3

DAPAgliflozin for Renal Protection in Heart Transplant Recipients

Kidney FailureHeart Transplant Failure
Oslo University Hospital430 enrolled6 locationsNCT05321706
Recruiting

Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients

Renal transplantDiagnosisKidney Transplant; Complications+5 more
Liverpool University Hospitals NHS Foundation Trust282 enrolled1 locationNCT06025240
Recruiting
Not Applicable

Efficiency of Everolimus for the Treatment of Kidney Transplanted Patients Presenting a Missing Self-induced NK-mediated Rejection

Kidney Transplant Failure and Rejection
Hospices Civils de Lyon20 enrolled1 locationNCT03955172
Recruiting

Serum GLYcomics to Predict Graft Loss and Mortality After Liver Transplantation

Liver Transplant FailurePrognostic Biomarkers
University Hospital, Ghent600 enrolled1 locationNCT05866796
Recruiting

The Transplant Cohort of the German Center for Infection Research

InfectionsImmunosuppressionTransplant Complication+1 more
Technical University of Munich3,000 enrolled1 locationNCT06346665
Recruiting

Tacrolimus and Personalized Therapy to Prevent Acute Rejection Episodes

Heart Transplant Failure
Fondazione IRCCS Policlinico San Matteo di Pavia25 enrolled1 locationNCT06338306
Recruiting
Not Applicable

Home Based Monitoring of Kidney Transplants Utilizing Capillary Microsamples

Kidney Transplant Failure and Rejection
Oslo University Hospital50 enrolled1 locationNCT04369612
Recruiting
Not Applicable

Cytokine Filtration in Lung Transplantation: A Swedish National Study (GLUSorb)

Lung Transplant; ComplicationsLung Transplant Failure
Lund University Hospital116 enrolled1 locationNCT05526950