Phase 2 Type 1 Diabetes Clinical Trials
32 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 32 trials
Recruiting
Phase 1Phase 2
A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes
Type 1 DiabetesNew Onset
City of Hope Medical Center120 enrolled11 locationsNCT07061574
Recruiting
Phase 1Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled31 locationsNCT06783309
Recruiting
Phase 1Phase 2
Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)
Type 1 Diabetes Mellitus
University of Chicago70 enrolled1 locationNCT06305286
Recruiting
Phase 1Phase 2
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 2
Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes
InsulinType 1 Diabetes (T1D)Glycemic Control for Diabetes Mellitus+2 more
University of Virginia40 enrolled1 locationNCT07186660
Recruiting
Phase 1Phase 2
Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes
Diabetes Mellitus, Type 1Type 1 Diabetes
Creative Medical Technology Holdings Inc18 enrolled1 locationNCT05626712
Recruiting
Phase 2
FrexalimAB in Preservation of Endogenous insULIN Secretion Compared to Placebo in adUlts and Adolescents on Top of inSulin Therapy (FABULINUS)
Type 1 Diabetes Mellitus
Sanofi192 enrolled80 locationsNCT06111586
Recruiting
Phase 2
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
Type 1 Diabetes
SAb Biotherapeutics, Inc.159 enrolled65 locationsNCT07187531
Recruiting
Phase 2
INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes
Type 1 Diabetes Mellitus
Mannkind Corporation100 enrolled2 locationsNCT07224321
Recruiting
Phase 2
Efficacy and Safety of Teplizumab in Japanese Participants With Stage 2 Type 1 Diabetes
Type 1 Diabetes Mellitus
Sanofi10 enrolled11 locationsNCT06791291
Recruiting
Phase 2
The Effect of Colchicine, on Insulin Sensitivity in Individuals With Type 1 Diabetes and Systemic Low-grade Inflammation
Type 1 DiabetesInsulin SensitivityChronic Inflammation
Asger Lund, MD26 enrolled1 locationNCT07247734
Recruiting
Phase 2
Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
Diabetes MellitusType 1 DiabetesDiabetes type1+1 more
Massachusetts General Hospital100 enrolled1 locationNCT05866536
Recruiting
Phase 2
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
Type 1 Diabetes Mellitus With Hypoglycemia
Zucara Therapeutics Inc.186 enrolled33 locationsNCT05762107
Recruiting
Phase 2
Precision Administration of Anti-thymocyte Globulin With or Without Verapamil
Type 1 Diabetes
University of Florida60 enrolled2 locationsNCT06455319
Recruiting
Phase 2
The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes
Type 1 DiabetesType 2 Diabetes
Mayo Clinic60 enrolled1 locationNCT06976619
Recruiting
Phase 1Phase 2
A Phase I/II Trial to Preserve Residual Insulin Secretion in Children With Recent Onset Type 1 Diabetes by Giving Verapamil
Type 1 Diabetes
Johnny Ludvigsson36 enrolled2 locationsNCT07199946
Recruiting
Phase 2
TArgeting Type 1 Diabetes Using POLyamines (TADPOL)
Type 1 Diabetes
Emily K. Sims70 enrolled7 locationsNCT05594563
Recruiting
Phase 2
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
Type 1 DiabetesDiabetic Kidney Disease
University of Washington60 enrolled4 locationsNCT05822609
Recruiting
Phase 2
Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes
Heart FailureType 1 Diabetes
University of Dundee320 enrolled15 locationsNCT06435156
Recruiting
Phase 1Phase 2
Denosumab for Type 1 Diabetes
Type 1 Diabetes
City of Hope Medical Center45 enrolled3 locationsNCT06524960