Phase 3 Type 1 Diabetes Clinical Trials

13 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 113 of 13 trials

Recruiting
Phase 3

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Type 1 Diabetes Mellitus
Sanofi723 enrolled141 locationsNCT07088068
Recruiting
Phase 2Phase 3

Open-Label Study of Dimethyl Fumarate in Adults With Type 1 Diabetes

Type 1 Diabetes Mellitus
Nanjing Medical University96 enrolled1 locationNCT07548996
Recruiting
Phase 3

An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

Kidney TransplantType 1 Diabetes
Vertex Pharmaceuticals Incorporated10 enrolled7 locationsNCT06832410
Recruiting
Phase 3

Clinical Study for Dimethyl Fumarate in Preserving Islet β-Cell Function in Type 1 Diabetes Mellitus

Type 1 Diabetes
Nanjing Medical University90 enrolled1 locationNCT07258394
Recruiting
Phase 3

GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes

Type 1 Diabetes (T1D)
University of Bern42 enrolled3 locationsNCT06630585
Recruiting
Phase 2Phase 3

Insulin Producing Stem Cell Transplantation Clinical Trial in Type 1 Diabetes

Type 1 DiabetesStem Cells
Ain Shams University20 enrolled1 locationNCT06951074
Recruiting
Phase 3

Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes

Heart FailureCardiovascular DiseasesType 1 Diabetes+1 more
Steno Diabetes Center Copenhagen2,000 enrolled2 locationsNCT06082063
Recruiting
Phase 2Phase 3

Alleviating Carbohydrate Counting for Patients with Type-1 Diabetes Using a Closed Loop System with Weekly Subcutaneous Semaglutide

Diabetes MellitusType 1 Diabetes
McGill University Health Centre/Research Institute of the McGill University Health Centre26 enrolled1 locationNCT06387199
Recruiting
Phase 2Phase 3

Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes

Type 1 Diabetes
Throne Biotechnologies Inc.50 enrolled2 locationsNCT04011020
Completed
Phase 3

Investigating the effect of oral insulin on glycaemia

Type 1 Diabetes
Child and Adolescent Health Service10 enrolled1 locationACTRN12622000764730
Completed
Phase 3

INTIMET: INsulin Resistance in Type 1 Diabetes Managed with METformin

Type 1 Diabetes
Garvan Institute of Medical Research60 enrolled2 locationsACTRN12619001440112
Completed
Phase 3

The effect of Hybrid Closed Loop insulin delivery on glucose control in patients with type 1 diabetes aged 12 - 25 years.

Type 1 Diabetes
Telethon Kids Institute160 enrolled6 locationsACTRN12616000753459
Active
Phase 3

The Fenofibrate And Microvascular Events in Type 1 diabetes Eye: A randomised trial to evaluate the efficacy on retinopathy and safety of fenofibrate in adults with type 1 diabete. A multicentre double-blind placebo-controlled study in Australia and internationally

Eye disease (retinopathy) in type 1 diabetes mellitusDiabetic nephropathy in type 1 diabetes mellitus
NHMRC Clinical Trials Centre, University of Sydney450 enrolled23 locationsACTRN12611000249954