Venous Malformation Clinical Trials

37 recruitingLast updated: July 25, 2026

There are 37 actively recruiting venous malformation clinical trials across 17 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Paris, France, Bordeaux, France, Tours, France. Updated daily from ClinicalTrials.gov.


Venous Malformation Trials at a Glance

37 actively recruiting trials for venous malformation are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Not Applicable with 12 trials, with the heaviest enrollment activity in Paris, Bordeaux, and Tours. Lead sponsors running venous malformation studies include Beijing Tiantan Hospital, Fondation Ophtalmologique Adolphe de Rothschild, and Hospices Civils de Lyon.

Browse venous malformation trials by phase

Treatments under study

About Venous Malformation Clinical Trials

Looking for clinical trials for Venous Malformation? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Venous Malformation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Venous Malformation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 37 trials

Recruiting
Phase 3

A Study to Investigate Efficacy and Safety of KP-001 Compared With Placebo in Patients Aged ≥2 Years With Common VM, Common LM, or KTS/CLOVES Syndrome

Venous malformationsLymphatic MalformationsCLOVES Syndrome+1 more
Kaken Pharmaceutical150 enrolled1 locationNCT07285005
Recruiting

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

Gastrointestinal BleedingTelangiectasiaArteriovenous Malformations+4 more
Cure HHT10,000 enrolled16 locationsNCT06259292
Recruiting

Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies

Noonan SyndromeCardiofaciocutaneous SyndromeCostello Syndrome+3 more
National Cancer Institute (NCI)500 enrolled2 locationsNCT04888936
Recruiting
Not Applicable

Exploratory Study of Cerebral Perfusion and Metabolic Alterations and Neurocognitive Disorders in Patients With Unruptured Arteriovenous Malformations Before and After Surgical Treatment

Unruptured Brain Arteriovenous Malformation
University Hospital, Montpellier10 enrolled1 locationNCT07569887
Recruiting

Cera™ Vascular Plug System Post-Market Clinical Follow-Up

Arteriovenous FistulaAneurysmPortal Hypertension+3 more
Lifetech Scientific (Shenzhen) Co., Ltd.132 enrolled9 locationsNCT06099015
Recruiting
Phase 2

Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous Malformations

Arteriovenous Malformations
Centre Hospitalier Universitaire, Amiens50 enrolled13 locationsNCT02042326
Recruiting

Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping

Intracranial AneurysmArteriovenous Malformations, Cerebral
University Hospital, Ghent500 enrolled1 locationNCT06588543
Recruiting
Phase 2

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations

PI3K Gene MutationKRAS G12DVascular Anomalies+15 more
Murdoch Childrens Research Institute50 enrolled2 locationsNCT05983159
Recruiting

Pulmonary Embolism and Right-to-Left Shunts

Pulmonary Embolism (PE)StrokePulmonary Arteriovenous Malformation+3 more
Tufts Medical Center256 enrolled1 locationNCT07519876
Recruiting

Neurosurgical Outcome Network

DepressionTrigeminal NeuralgiaObsessive-Compulsive Disorder+20 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta4,500 enrolled27 locationsNCT06724029
Recruiting
Not Applicable

PHIL® Embolic System Pediatric IDE

Intracranial Arteriovenous MalformationsArterio-venous Fistula
Alejandro Berenstein15 enrolled1 locationNCT03731000
Recruiting

Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study

Arteriovenous MalformationsVascular AnomalyOsler Rendu Disease+3 more
Hospices Civils de Lyon400 enrolled36 locationsNCT04194619
Recruiting
Phase 2

Weekly Sirolimus Therapy

Lymphatic MalformationVenous Malformation
Medical University of South Carolina24 enrolled1 locationNCT04861064
Recruiting
Not Applicable

Efficacy & Safety of LOBO™ Vascular Occlusion Device for Embolization of Pulmonary Arteriovenous Malformations

Pulmonary Arteriovenous Malformations
University of North Carolina, Chapel Hill30 enrolled1 locationNCT06735976
Recruiting
Not Applicable

Non-Invasive Detection of Pulmonary Right-to-Left Shunts Using the SONAS Ultrasound Device

Hereditary Haemorrhagic TelangiectasiaPulmonary Arteriovenous MalformationPFO - Patent Foramen Ovale
St. Antonius Hospital40 enrolled1 locationNCT07414446
Recruiting

Genetics of Central Nervous System Arteriovenous Malformations (GENE-MAV)

Arteriovenous Malformations
Fondation Ophtalmologique Adolphe de Rothschild300 enrolled1 locationNCT04772963
Recruiting

Long Term Follow-up After Embolization of Brain Arteriovenous Malformations

Arteriovenous Malformations
Fondation Ophtalmologique Adolphe de Rothschild1,000 enrolled1 locationNCT02879071
Recruiting
Not Applicable

The Liquid Embolic Agent for the Treatment of Brain Arteriovenous Malformation

Arteriovenous FistulaBrain Arteriovenous Malformation
MicroPort NeuroTech Co., Ltd.116 enrolled1 locationNCT07314047
Recruiting

Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform

Acute Ischemic StrokeBrain Arterial DiseaseIntracranial Aneurysm+4 more
Balt Extrusion10,000 enrolled12 locationsNCT04927156
Recruiting

Clinical Study on Emergency Treatment of Cerebral Arteriovenous Malformation Bleeding

BleedingArteriovenous Malformation
Beijing Tiantan Hospital162 enrolled1 locationNCT07118631