Phase 3 Wound Clinical Trials

22 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 22 trials

Recruiting
Phase 3

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

Wound HealWound ComplicationWound Dehiscence+2 more
Major Extremity Trauma Research Consortium352 enrolled6 locationsNCT06337292
Recruiting
Phase 2Phase 3

Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients

Burn scarBurn Wound
Birch BioMed Inc70 enrolled2 locationsNCT06807021
Recruiting
Phase 3

Tissue Repair Gel in Venous Leg Ulcers (US)

WoundsWound HealVenous Ulcer+5 more
TR Therapeutics312 enrolled33 locationsNCT06707090
Recruiting
Phase 3

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 3

A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer

WoundDiabetes MellitusDiabetic Foot Ulcer+1 more
Energenesis Biomedical Co., Ltd.230 enrolled24 locationsNCT05930210
Recruiting
Phase 3

Novel Strategies for Reducing Burn Scar Itch

WoundBurn scarItch Scarring
The University of Texas Medical Branch, Galveston44 enrolled1 locationNCT06801626
Recruiting
Phase 3

The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal

Surgical wound infection
The Cooper Health System848 enrolled1 locationNCT07142408
Recruiting
Phase 3

Trauma Resuscitation With Low-Titer Group O Whole Blood or Products

Wounds and InjuriesShock, Hemorrhagic
University of Alabama at Birmingham1,100 enrolled13 locationsNCT05638581
Recruiting
Phase 3

ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients

Multiple traumaTraumatic Brain InjuryWounds and Injuries+5 more
Australian and New Zealand Intensive Care Research Centre2,500 enrolled41 locationsNCT04588311
Recruiting
Phase 2Phase 3

Human Penile Allotransplantation

Wounds and InjuriesAmputationAmputation, Traumatic+6 more
Johns Hopkins University60 enrolled1 locationNCT02395497
Recruiting
Phase 2Phase 3

Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

SeromaSurgical Site InfectionSurgical Wound+5 more
Dow University of Health Sciences200 enrolled1 locationNCT05989386
Recruiting
Phase 3

Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

Wound HealBurn Degree SecondBurns Degree Third+2 more
XenoTherapeutics, Inc.50 enrolled4 locationsNCT06223269
Recruiting
Phase 3

Tissue Repair Gel in Venous Leg Ulcers in AU/US

WoundWound HealVenous Ulcer+5 more
TR Therapeutics312 enrolled12 locationsNCT06707103
Recruiting
Phase 3

Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery

Surgical wound infectionAnesthesiaPathologic Processes+9 more
University of Birmingham12,942 enrolled37 locationsNCT04256798
Recruiting
Phase 2Phase 3

Multicenter Study Protocol: Research on Evaluation and Detection of Surgical Wound Complications with AI-based Recognition. (REDSCAR-trial)

Surgical wound infection
Universitat de les Illes Balears168 enrolled5 locationsNCT06771726
Recruiting
Phase 3

Effects of Topical Insulin on Corneal Epithelium Healing After Corneal Crosslinking in Patients With Keratoconus

Wound HealEye DiseasesKeratoconus+1 more
University of Campinas, Brazil36 enrolled1 locationNCT06601101
Recruiting
Phase 3

The Role of Antibiotic Prophylaxis in Lowering Wound Infection Rates Post-Open Repair of Primary Elective Groin Hernias in High-Risk Patients

Groin HerniaAntibiotic ProphylaxisWound Infection
University of Aleppo200 enrolled1 locationNCT06576154
Recruiting
Phase 2Phase 3

Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy

Opioid UseMorbid ObesityTransversus Abdominis Plane Block+3 more
Khon Kaen University98 enrolled1 locationNCT05930184
Completed
Phase 3

The efficacy of low-frequency ultrasonic debridement (LFUD) and Polyhexamethylene Biguanide (PHMB) combination therapy for adults with chronic wounds; a randomised controlled trial

Chronic wounds
Marianne Wallis50 enrolled1 locationACTRN12617001291370
Not Yet Recruiting
Phase 3

A pilot randomised clinical trial: flucloxacillin plus probenecid versus flucloxacillin alone for uncomplicated skin infections

Cellulitisinfected wound
Nelson Bays Primary Health100 enrolled1 locationACTRN12614000996662