Interleukin-2 Clinical Trials
25 recruitingDrug
Phase 117Phase 217Early Phase 11Phase 31
Showing 1–20 of 25 trials
Recruiting
Phase 2
IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients
Melanoma Stage IVInoperable DiseaseMelanoma Stage III
H. Lee Moffitt Cancer Center and Research Institute29 enrolled1 locationNCT04562129
Recruiting
Phase 1Phase 2
Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma
Melanoma
H. Lee Moffitt Cancer Center and Research Institute36 enrolled1 locationNCT06961357
Recruiting
Phase 1
CIML NK Cells With Venetoclax for AML
Acute Myeloid LeukemiaLeukemiaLeukemia, Myeloid+1 more
Dana-Farber Cancer Institute10 enrolled2 locationsNCT06152809
Recruiting
Phase 2
TIL Therapy in cSCC and MCC
Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaSkin Cancer+1 more
Karam Khaddour, MD, MS14 enrolled1 locationNCT07288073
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors
Select Advanced Solid Tumors
M.D. Anderson Cancer Center141 enrolled1 locationNCT06598371
Recruiting
Phase 1
Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease
Pleural Effusion, MalignantMalignant MesotheliomaMalignant Pleural Effusion+1 more
David Bartlett, MD10 enrolled1 locationNCT07192900
Recruiting
Phase 1
Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation
Acute Myeloid LeukemiaLeukemiaMyelodysplastic Syndromes+3 more
Dana-Farber Cancer Institute15 enrolled2 locationsNCT06138587
Recruiting
Phase 1Phase 2
A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC
Metastatic Colorectal CancerProstate Cancer MetastaticProstate Cancer Locally Advanced
Curacell Holding AB12 enrolled1 locationNCT07255664
Recruiting
Phase 2
Quadruple Immunotherapy for Neuroblastoma
Neuroblastoma Recurrent
Hong Kong Children's Hospital29 enrolled1 locationNCT05754684
Recruiting
Phase 2
Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study
Rectal Cancer
The First Affiliated Hospital with Nanjing Medical University130 enrolled4 locationsNCT06884670
Recruiting
Phase 1Phase 2
IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers
Multiple MyelomaNHLRefractory Non-Hodgkin Lymphoma+1 more
Indapta Therapeutics, INC.128 enrolled12 locationsNCT06119685
Recruiting
Phase 1Phase 2
TIL Gean Therapy Combined With Immunotherapy for Advanced or Metastatic Refractory Breast Cancer
Breast CancerBreast Cancer MetastaticBreast Carcinoma+1 more
Essen Biotech85 enrolled1 locationNCT06532812
Recruiting
Phase 1Phase 2
TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and Esophageal Cancer
Esophageal CancerStomach CancerStomach Cancer Recurrent+4 more
Essen Biotech75 enrolled1 locationNCT06532799
Recruiting
Early Phase 1
Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors
Epithelial Tumors, MalignantMalignant Solid Tumor
Vall d'Hebron Institute of Oncology10 enrolled1 locationNCT05141474
Recruiting
Phase 1Phase 2
TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas
Brain MetastasesBrain TumorBrain Cancer+4 more
Essen Biotech85 enrolled1 locationNCT06640582
Recruiting
Phase 1Phase 2
Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer
Essen Biotech85 enrolled1 locationNCT06530303
Recruiting
Phase 1Phase 2
TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer
Lung CancerLung Cancer Metastatic
Essen Biotech85 enrolled1 locationNCT06538012
Recruiting
Phase 2
A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.
Soft Tissue SarcomaNeuroendocrine TumorsVaccination+2 more
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS51 enrolled1 locationNCT04166006
Recruiting
Phase 1
Individualized Tumor Specific TCR- T Cells in the Treatment of Advanced Solid Tumors
Solid Tumor
Guangzhou FineImmune Biotechnology Co., LTD.30 enrolled1 locationNCT03891706
Recruiting
Phase 2
Phase II Clinical Trial of Interleukin-2 in AD
Alzheimer Disease
The Methodist Hospital Research Institute40 enrolled1 locationNCT06096090