TIL Therapy in cSCC and MCC

This trial is testing tumor-infiltrating lymphocyte (TIL) therapy — a treatment where immune cells are taken from your tumor, multiplied in a lab, and infused back into your body to fight the cancer — for two types of skin cancer: cutaneous squamous cell carcinoma (cSCC) and Merkel cell carcinoma (MCC). **You may be eligible if...** - You are 18 or older - You have a confirmed diagnosis of cSCC or MCC that cannot be surgically removed or has returned or spread - You have measurable disease visible on imaging - You are willing to undergo the intensive treatment process (including cell collection, chemotherapy conditioning, and infusion) **You may NOT be eligible if...** - Your cancer can still be surgically removed - You are not able to tolerate intensive supportive medical care - You have significant organ dysfunction - You are not willing to consent to the intensive nature of the procedure Talk to your doctor to see if this trial is right for you.