Leiden University Medical Center
Leiden, Netherlands
41 recruiting
Showing 1–20 of 41 trials
Recruiting
Phase 1Phase 2
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
Non-small Cell Lung Cancer (NSCLC)KRAS, NRAS, HRAS-mutated NSCLCKRAS G12C-mutated Solid Tumors, Lung Cancer+2 more
Revolution Medicines, Inc.616 enrolled89 locationsNCT06162221
Recruiting
Phase 3
Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma
High-risk Large B-cell Lymphoma (LBCL)
Kite, A Gilead Company300 enrolled90 locationsNCT05605899
Recruiting
Phase 3
Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases
Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817
Recruiting
Determining Prognostic Immune Markers in Patients With Ovarian Cancer
Epithelial Ovarian Cancer
Leiden University Medical Center300 enrolled1 locationNCT03862677
Recruiting
Phase 3
Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations
Metastatic Non Small Cell Lung Cancer
Daiichi Sankyo740 enrolled243 locationsNCT05215340
Recruiting
Phase 1Phase 2
MB-dNPM1-TCR.1 in Relapsed/Refractory AML
Leukemia, Myeloid, Acute
Miltenyi Biomedicine GmbH29 enrolled1 locationNCT06424340
Recruiting
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study)
Type1 Diabetes Mellitus
University of Exeter300 enrolled4 locationsNCT03369821
Recruiting
Phase 3
Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.
Oropharyngeal Squamous Cell CarcinomaLaryngeal Squamous Cell CarcinomaHypopharynx Squamous Cell Carcinoma
Radboud University Medical Center242 enrolled9 locationsNCT05333523
Recruiting
Not Applicable
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
Ovarian CancerBRCA1 Gene MutationBRCA2 Gene Mutation+3 more
University Medical Center Nijmegen3,000 enrolled48 locationsNCT04294927
Recruiting
Oncological Safety of Spleen Preservation in Left Pancreatectomy for Pancreatic Ductal Adenocarcinoma (SPLENDID)
Pancreatic Cancer ResectablePancreatectomy
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)94 enrolled10 locationsNCT07157605
Recruiting
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
Chronic Spontaneous Urticaria (CSU)Hidradenitis Suppurativa (HS)Psoriasis (PsO)+2 more
Leiden University Medical Center840 enrolled8 locationsNCT07021495
Recruiting
Not Applicable
Smart Measurement of Circulating Tumor DNA
Colorectal NeoplasmsColorectal Neoplasms MalignantColorectal Neoplasms, Hereditary Nonpolyposis+1 more
Erasmus Medical Center50 enrolled2 locationsNCT06989814
Recruiting
The Impact of Endoscopic Endonasal Skull Base Surgery on Olfaction
MeningiomaPituitary AdenomaCraniopharyngioma+3 more
Universitaire Ziekenhuizen KU Leuven154 enrolled3 locationsNCT06874426
Recruiting
Prospective Registration Of Patient Data and Quality of Life in Eye Melanoma Patients
Uveal Melanoma
Leiden University Medical Center500 enrolled1 locationNCT05377957
Recruiting
Vascular Signature Mapping of Brain Tumor Genotypes
Glioma
Leiden University Medical Center180 enrolled2 locationsNCT05274919
Recruiting
Phase 4
Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4
Chronic Kidney DiseaseDiet ModificationHyperkalemia+1 more
Leiden University Medical Center16 enrolled1 locationNCT06365684
Recruiting
Phase 2
FUnctional Selection of Advanced Breast Cancer Patients for Talazoparib Treatment Using the REpair Capacity (RECAP) Test
Advanced Breast Cancer
Erasmus Medical Center66 enrolled3 locationsNCT06193525
Recruiting
Phase 1
Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists
Opioid Induced Respiratory DepressionChronic Opioid Use
Leiden University Medical Center24 enrolled1 locationNCT05338632
Recruiting
Phase 4
Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose
Liver DiseasesCirrhosis, LiverPortal Hypertension+2 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)238 enrolled6 locationsNCT04073290
Recruiting
Not Applicable
EMDR for Fear of Cancer Recurrence in Patients with Familial Melanoma: a Waiting List Control Trial
Familial MelanomaFear of Cancer RecurrenceEye Movement Desensitization and Reprocessing+1 more
Leiden University Medical Center30 enrolled2 locationsNCT06767332