Leiden University Medical Center

Leiden, Netherlands

41 recruiting

Showing 120 of 104 trials

Recruiting
Phase 2

Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer

Lung Cancer - Non Small Cell SquamousLung Cancer - Non Small Cell Non-Squamous
Merus B.V.180 enrolled24 locationsNCT07353957
Recruiting
Phase 3

A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Thrombocytopenia, Neonatal Alloimmune
Janssen Research & Development, LLC50 enrolled26 locationsNCT06533098
Recruiting
Phase 3

A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

Hemolytic Disease of the Fetus and Newborn
Janssen Research & Development, LLC120 enrolled62 locationsNCT05912517
Recruiting
Phase 2Phase 3

A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis
argenx12 enrolled20 locationsNCT06392386
Recruiting
Phase 3

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

Alpha 1-Antitrypsin Deficiency
Grifols Therapeutics LLC40 enrolled19 locationsNCT07555483
Recruiting
Phase 4

Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism

Cardiovascular DiseasesVenous ThromboembolismPulmonary Embolism+6 more
Drahomir Aujesky276 enrolled40 locationsNCT04263038
Recruiting

Results of Nerve Surgery to Treat PostAmputation Pain

Amputation Neuroma
Leiden University Medical Center98 enrolled1 locationNCT07605754
Recruiting
Phase 3

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

Metastatic Non Small Cell Lung Cancer
Daiichi Sankyo740 enrolled243 locationsNCT05215340
Recruiting
Phase 3

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Alpha1-Antitrypsin Deficiency
Takeda160 enrolled89 locationsNCT05677971
Recruiting

Met Non Small Cell Cancer Registry (MOMENT)

Cancer
EMD Serono Research & Development Institute, Inc.700 enrolled64 locationsNCT05376891
Recruiting

SPECTATOR: Perfusion Monitoring Before, During and After Lower Extremity Revascularization With Laser Speckle Contrast Imaging

Vascular Disease,Peripheral
Leiden University Medical Center30 enrolled1 locationNCT07558174
Recruiting

Bleeding Disorder of Unknown Cause in the Netherlands

Hemorrhagic DisordersBleeding Disorder of Unknown Cause
Maastricht University Medical Center500 enrolled8 locationsNCT07454161
Recruiting
Phase 3

A Long-term Follow-up Trial of Patients Previously Treated With Imlifidase Prior to Kidney Transplantation and a Non-comparative Transplanted Patient Group

Long Term Efficacy and Safety
Hansa Biopharma AB150 enrolled14 locationsNCT05937750
Recruiting
Phase 1Phase 2

MB-dNPM1-TCR.1 in Relapsed/Refractory AML

Leukemia, Myeloid, Acute
Miltenyi Biomedicine GmbH29 enrolled1 locationNCT06424340
Recruiting
Not Applicable

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Heart DiseasesCoronary Artery DiseaseCoronary Artery Bypass Grafting
Weill Medical College of Cornell University2,300 enrolled146 locationsNCT04124120
Recruiting
Not Applicable

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

Ovarian CancerBRCA1 Gene MutationBRCA2 Gene Mutation+3 more
University Medical Center Nijmegen3,000 enrolled66 locationsNCT04294927
Recruiting
Phase 2Phase 3

A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis

Myasthenia Gravis
Janssen Research & Development, LLC12 enrolled19 locationsNCT05265273
Recruiting
Phase 1Phase 2

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

Non-small Cell Lung Cancer (NSCLC)KRAS, NRAS, HRAS-mutated NSCLCKRAS G12C-mutated Solid Tumors, Lung Cancer+2 more
Revolution Medicines, Inc.616 enrolled89 locationsNCT06162221
Recruiting
Phase 3

Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma

High-risk Large B-cell Lymphoma (LBCL)
Kite, A Gilead Company300 enrolled90 locationsNCT05605899
Recruiting
Phase 3

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817