Massachusetts General Hospital

Boston, Massachusetts, United States

323 recruiting

Showing 120 of 746 trials

Recruiting
Phase 3

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Immune Thrombocytopenic Purpura (ITP)
Takeda171 enrolled114 locationsNCT06722235
Recruiting

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

Genetic Disease
National Human Genome Research Institute (NHGRI)20,000 enrolled33 locationsNCT02450851
Recruiting
Phase 3

The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

Bronchiectasis
Boehringer Ingelheim1,755 enrolled470 locationsNCT06872892
Recruiting
Phase 3

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic Ductal Adenocarcinoma (PDAC)
SOFIE200 enrolled15 locationsNCT07217717
Recruiting
Phase 2

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

Myasthenia GravisGeneralized Myasthenia Gravis (gMG)Generalized Myasthenia Gravis+3 more
argenx70 enrolled24 locationsNCT07284420
Recruiting
Phase 3

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

Esophageal CancerGastric Cancer (GC)Gastroesophageal Junction
SOFIE200 enrolled15 locationsNCT07217704
Recruiting
Phase 1

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

Breast CancerColorectal, CancerEsophageal Cancer+3 more
Immunome, Inc.175 enrolled2 locationsNCT07578571
Recruiting

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

Myasthenia GravisGeneralized Myasthenia Gravis (gMG)Generalized Myasthenia Gravis+3 more
argenx70 enrolled29 locationsNCT07294170
Recruiting
Phase 3

A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

Interstitial Lung DiseasesSystemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases
Boehringer Ingelheim400 enrolled156 locationsNCT06806592
Recruiting
Not Applicable

Zenith® Fenestrated+ Clinical Study

Juxtarenal Aortic AneurysmAortic Aneurysm, AbdominalPararenal Aneurysm+1 more
Cook Research Incorporated105 enrolled33 locationsNCT04875429
Recruiting
Phase 3

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

Systemic Sclerosis
Boehringer Ingelheim448 enrolledNCT07497087
Recruiting
Phase 2

The Progressive Supranuclear Palsy Clinical Trial Platform

Progressive Supranuclear Palsy (PSP)
Adam Boxer440 enrolledNCT07173803
Recruiting
Phase 1Phase 2

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

Breast CancerOvarian CancerCervical Cancer+5 more
Terremoto Biosciences Inc.205 enrolled15 locationsNCT07109726
Recruiting
Phase 3

A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata

Alopecia Areata
Pfizer674 enrolled114 locationsNCT06873945
Recruiting

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

Parkinson's Disease
Boston Scientific Corporation1,500 enrolled85 locationsNCT02071134
Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled22 locationsNCT07326566
Recruiting
Phase 1

A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

Primary Myelofibrosis
Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company256 enrolled21 locationsNCT06343805
Recruiting
Phase 1Phase 2

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Breast CancerTriple-Negative Breast CancerColorectal, Cancer+26 more
PMV Pharmaceuticals, Inc300 enrolled77 locationsNCT04585750
Recruiting
Phase 3

Pridopidine Phase 3 Study in Huntington's Disease

Huntington Disease
Prilenia400 enrolledNCT07609108
Recruiting
Phase 3

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

Status Epilepticus
University of Virginia770 enrolled52 locationsNCT06907173