Massachusetts General Hospital
Boston, Massachusetts, United States
323 recruiting
Showing 1–20 of 323 trials
Recruiting
Phase 3
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Urinary Bladder NeoplasmsNeoplasm MetastasisCarcinoma, Transitional Cell
Eli Lilly and Company450 enrolled279 locationsNCT07218380
Recruiting
Phase 1Phase 2
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
Relapsed/Refractory Multiple Myeloma
BeOne Medicines246 enrolled83 locationsNCT04973605
Recruiting
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
Parkinson Disease
Michael J. Fox Foundation for Parkinson's Research4,500 enrolled50 locationsNCT04477785
Recruiting
Phase 1Phase 2
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
Advanced Solid TumorNon-small Cell Lung CancerUntreated Advanced NSCLC+1 more
Synthekine364 enrolled27 locationsNCT05098132
Recruiting
Not Applicable
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Metabolic SyndromeDiabetes Mellitus, Type 2Prediabetes
Cleerly, Inc.7,500 enrolled115 locationsNCT06112418
Recruiting
Not Applicable
A Digital Health Intervention to Improve Physical Function and Wellness of Lung Cancer Survivors
Advanced Lung CancerPhysical Function
Massachusetts General Hospital250 enrolled1 locationNCT07227623
Recruiting
Phase 2
Study of COYA 302 for the Treatment of ALS
Amyotrophic Lateral Sclerosis(ALS)
Coya Therapeutics120 enrolled24 locationsNCT07161999
Recruiting
Not Applicable
ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence
Insulin ResistancePhysical ActivityPCOS (Polycystic Ovary Syndrome)+1 more
Massachusetts General Hospital40 enrolled1 locationNCT07102797
Recruiting
Phase 4
Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs
HIVSubstance Use Disorder (SUD)Injection Drug Use
Massachusetts General Hospital100 enrolled2 locationsNCT07199335
Recruiting
Phase 1
Ziftomenib Maintenance Post Allo-HCT
Acute Myeloid LeukemiaAcute Myeloid Leukemia in RemissionKMT2A Rearrangement+1 more
Massachusetts General Hospital22 enrolled2 locationsNCT06440135
Recruiting
Phase 3
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S1,280 enrolled285 locationsNCT07207811
Recruiting
Phase 4
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
Multiple Myeloma
Janssen Research & Development, LLC295 enrolled50 locationsNCT05201781
Recruiting
Phase 1
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
Metastatic Breast CancerAdvanced Breast CancerMetastatic Lung Cancer+8 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)392 enrolled32 locationsNCT06625775
Recruiting
Phase 1Phase 2
Proton or Photon RT for Retroperitoneal Sarcomas
Retroperitoneal Sarcoma
Massachusetts General Hospital80 enrolled10 locationsNCT01659203
Recruiting
Phase 1
A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs
Mabwell (Shanghai) Bioscience Co., Ltd.52 enrolled6 locationsNCT06908928
Recruiting
Phase 1
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Non-small Cell Lung CancerNSCLCMetastatic Pancreatic Ductal Adenocarcinoma+11 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)387 enrolled10 locationsNCT06917079
Recruiting
Phase 2
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Large B-cell Lymphoma
Allogene Therapeutics250 enrolled61 locationsNCT06500273
Recruiting
Not Applicable
Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections
Postoperative ComplicationsAnastomotic LeaksAnastomotic Complication+8 more
Medtronic - MITG137 enrolled8 locationsNCT07351071
Recruiting
Phase 3
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.
Esophageal CancerGastric Cancer (GC)Gastroesophageal Junction
SOFIE200 enrolled10 locationsNCT07217704
Recruiting
Phase 1
CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma
Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaNon-Hodgkin Lymphoma+7 more
Marcela V. Maus, M.D.,Ph.D.24 enrolled1 locationNCT06026319