Radboud University Medical Center
Nijmegen, Netherlands
28 recruiting
Showing 1–20 of 28 trials
Recruiting
Phase 3
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Familial Adenomatous Polyposis (FAP)
Rapamycin Holdings Inc.168 enrolled26 locationsNCT06950385
Recruiting
Phase 3
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
Ovarian Cancer
Incyte Corporation466 enrolled133 locationsNCT07214779
Recruiting
Phase 1
A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies
Diffuse Large B-Cell Lymphoma (DLBCL)Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)+6 more
Nurix Therapeutics, Inc.572 enrolled62 locationsNCT05131022
Recruiting
Phase 3
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Colorectal Neoplasms
Janssen Research & Development, LLC700 enrolled229 locationsNCT06750094
Recruiting
Phase 3
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Colorectal Neoplasms
Janssen Research & Development, LLC1,000 enrolled231 locationsNCT06662786
Recruiting
Phase 3
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
Non-small Cell Lung CancerAnaplastic Lymphoma Kinase-positive
Nuvalent Inc.450 enrolled112 locationsNCT06765109
Recruiting
Phase 3
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV220 enrolled10 locationsNCT06451757
Recruiting
Phase 2
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Phase 1
A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia
Chronic Myeloid LeukemiaCMLChronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive
Enliven Therapeutics200 enrolled46 locationsNCT05304377
Recruiting
Not Applicable
The TASTY-steering Study
Metastatic Triple Negative Breast Cancer or Metastatic Testicular Cancer, or Stage II-IV Diffuse Large B Cell Lymphoma
University Medical Center Groningen201 enrolled11 locationsNCT07258563
Recruiting
Phase 1Phase 2
NEOadjuvant Dendritic Cell Vaccination for Ovarian Cancer
Ovarian CarcinomaEpithelial Ovarian Cancer
Radboud University Medical Center10 enrolled1 locationNCT05773859
Recruiting
Not Applicable
The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study
Aortic Stenosis
University of Leicester2,844 enrolled110 locationsNCT04204915
Recruiting
Phase 3
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Crohn's DiseaseUlcerative Colitis
Takeda70 enrolled57 locationsNCT06100289
Recruiting
Phase 2
Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab
NeoplasmsNeoplasms by SiteUrinary Bladder Neoplasm+8 more
The Netherlands Cancer Institute90 enrolled9 locationsNCT06237920
Recruiting
Phase 1Phase 2
Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC
PDAC
Anocca AB96 enrolled8 locationsNCT07145450
Recruiting
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
Chronic Spontaneous Urticaria (CSU)Hidradenitis Suppurativa (HS)Psoriasis (PsO)+2 more
Leiden University Medical Center840 enrolled8 locationsNCT07021495
Recruiting
Not Applicable
Stereotactic Body Radiation Therapy After Chemotherapy for Unresectable Perihilar Cholangiocarcinoma
Klatskin Tumor
Erasmus Medical Center30 enrolled8 locationsNCT06493734
Recruiting
Not Applicable
Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands
Brain DiseasesCentral Nervous System DiseasesParkinson Disease+8 more
Radboud University Medical Center110 enrolled1 locationNCT06193252
Recruiting
Phase 3
A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease
Crohn's Disease
Takeda396 enrolled138 locationsNCT06227910
Recruiting
Phase 3
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
Metastatic Head and Neck Squamous Cell CarcinomaRecurrent Head and Neck Squamous Cell Carcinoma
AVEO Pharmaceuticals, Inc.410 enrolled110 locationsNCT06064877