Radboud University Medical Center

Nijmegen, Netherlands

28 recruiting

Showing 120 of 69 trials

Recruiting
Phase 2

Open Label Extension to Assess Long Term Safety and Efficacy of KL1333 in Patients With Primary Mitochondrial Disease

Mitochondrial Diseases
Pharming Technologies B.V.140 enrolledNCT07514338
Recruiting
Phase 2

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled85 locationsNCT06172478
Recruiting
Phase 3

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Ovarian Cancer
Incyte Corporation466 enrolled178 locationsNCT07214779
Recruiting
Phase 3

A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

Essential Thrombocythemia
Incyte Corporation426 enrolledNCT07623200
Recruiting

A Prospective, Multicenter, Single-arm MAC-PD Cohort: a NTM-NET and ESGMYC Collaborative Study

Mycobacterium Avium Complex Pulmonary Disease
Radboud University Medical Center100 enrolled11 locationsNCT05906316
Recruiting
Phase 4

Hypertonic Saline Inhalation for Mycobacterium Avium Complex Pulmonary Disease

Nontuberculous Mycobacterial Lung DiseaseMycobacterium Avium Complex
Radboud University Medical Center30 enrolled1 locationNCT05192057
Recruiting
Phase 1Phase 2

A Phase 1b/2a Trial to Evaluate Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care.

Shock, Cardiogenic
4TEEN4 Pharmaceuticals GmbH90 enrolled25 locationsNCT06832722
Recruiting

Prospective Prostate Cancer Infrastructure

High-Risk Localized Prostate CancerSynchronous Metastatic Hormone-Sensitive Prostate Cancer
Radboud University Medical Center700 enrolledNCT07560748
Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

Retinitis PigmentosaInherited Retinal Degeneration
Jaeb Center for Health Research1,500 enrolled36 locationsNCT05589714
Recruiting
Phase 3

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

Myotonic DystrophyDM1Steinert Disease+2 more
Dyne Therapeutics150 enrolled20 locationsNCT07486934
Recruiting
Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms
Janssen Research & Development, LLC1,000 enrolled238 locationsNCT06662786
Recruiting
Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Colorectal Neoplasms
Janssen Research & Development, LLC700 enrolled250 locationsNCT06750094
Recruiting

Affordable, Tailored Physical Therapy for Financially Vulnerable People With Trauma-related Injuries (AFTER-TRAUMA)

PROMsQuality of Life
Radboud University Medical Center153 enrolledNCT07795216
Recruiting
Not Applicable

Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands

Brain DiseasesCentral Nervous System DiseasesParkinson Disease+8 more
Radboud University Medical Center110 enrolled1 locationNCT06193252
Recruiting
Not Applicable

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Brain DiseasesCentral Nervous System DiseasesGenetic Predisposition+8 more
Radboud University Medical Center600 enrolledNCT06993142
Recruiting
Phase 3

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Non-small Cell Lung CancerAnaplastic Lymphoma Kinase-positive
Nuvalent Inc.450 enrolled157 locationsNCT06765109
Recruiting
Early Phase 1

TGW211 for Click-Cleavable Imaging in HER2-Positive Cancers.

HER2-Positive Solid Tumor
Radboud University Medical Center19 enrolled1 locationNCT07009184
Recruiting

A Study on How the Immune System Responds to Sepsis and Its Long-term Effects

Sepsis
Radboud University Medical Center400 enrolled1 locationNCT07273344
Recruiting
Phase 4

Methylphenidate in KBG Syndrome: N-of-1 Series

ADHD - Combined TypeKbg Syndrome
Radboud University Medical Center15 enrolled1 locationNCT06465641
Recruiting
Phase 3

Utility of Adjusting Chemotherapy Dose & Dosing Schedule With the SALVage Weekly Dose-dense Regimen in Patients With Poor Prognostic OVARian Cancers Based on the Tumor Unfavorable Primary Chemosensitivity and Incomplete Debulking Surgery

Ovarian Cancer
ARCAGY/ GINECO GROUP250 enrolled72 locationsNCT06476184