Radboud University Medical Center

Nijmegen, Netherlands

28 recruiting

Showing 120 of 61 trials

Recruiting
Phase 3

Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Ovarian Cancer
Incyte Corporation466 enrolled157 locationsNCT07214779
Recruiting

Bleeding Disorder of Unknown Cause in the Netherlands

Hemorrhagic DisordersBleeding Disorder of Unknown Cause
Maastricht University Medical Center500 enrolled8 locationsNCT07454161
Recruiting
Phase 1Phase 2

Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care

Shock, Cardiogenic
4TEEN4 Pharmaceuticals GmbH130 enrolled20 locationsNCT06832722
Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

Retinitis PigmentosaInherited Retinal Degeneration
Jaeb Center for Health Research1,500 enrolled36 locationsNCT05589714
Recruiting
Phase 1

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Diffuse Large B-Cell Lymphoma (DLBCL)Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)+6 more
Nurix Therapeutics, Inc.572 enrolled62 locationsNCT05131022
Recruiting
Phase 2

Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

Primary Mitochondrial Disease
Abliva AB180 enrolled35 locationsNCT05650229
Recruiting
Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Colorectal Neoplasms
Janssen Research & Development, LLC700 enrolled234 locationsNCT06750094
Recruiting
Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms
Janssen Research & Development, LLC1,000 enrolled234 locationsNCT06662786
Recruiting
Phase 3

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

Metastatic Head and Neck Squamous Cell CarcinomaRecurrent Head and Neck Squamous Cell Carcinoma
AVEO Pharmaceuticals, Inc.410 enrolled112 locationsNCT06064877
Recruiting
Phase 1

A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia

Chronic Myeloid LeukemiaCMLChronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive
Enliven Therapeutics250 enrolled45 locationsNCT05304377
Recruiting
Phase 3

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Non-small Cell Lung CancerAnaplastic Lymphoma Kinase-positive
Nuvalent Inc.450 enrolled137 locationsNCT06765109
Recruiting
Phase 3

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis (FAP)
Rapamycin Holdings Inc.168 enrolled26 locationsNCT06950385
Recruiting

Multicenter Registry of Patients With Subarachnoid Hemorrhage

Subarachnoid Hemorrhage, Spontaneous
UMC Utrecht1,000 enrolled9 locationsNCT07482124
Recruiting
Not Applicable

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

Aortic AneurysmAortic DiseasesAortic Aneurysm and Dissection+3 more
Vascutek Ltd.150 enrolled23 locationsNCT07078383
Recruiting
Phase 3

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV220 enrolled10 locationsNCT06451757
Recruiting
Not Applicable

Use of Mechanical Left ventricuLar Unloading in Complex Higher-risk Indicated Procedures

High-risk PCICoronary Artery Disease Risk High
Amsterdam UMC, location VUmc98 enrolled8 locationsNCT07380217
Recruiting
Phase 2

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Not Applicable

The N-LVA Study: RCT Comparing LVA vs. Sham Surgery in Cancer-related Lymphedema

Lymphedema ArmLymphedema of Upper LimbLymphedema, Secondary+2 more
Maastricht University Medical Center110 enrolled3 locationsNCT06082349
Recruiting
Not Applicable

Pediatric Expansion Study of the Sentio System

Hearing Loss, Conductive
Oticon Medical50 enrolled8 locationsNCT06976086
Recruiting

Polycystic Liver Disease Registry (UK)

Polycystic Liver Disease
Portsmouth Hospitals NHS Trust500 enrolled2 locationsNCT04645251