Radboud University Medical Center
Nijmegen, Netherlands
28 recruiting
Showing 1–20 of 62 trials
Recruiting
Phase 3
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Crohn's DiseaseUlcerative Colitis
Takeda70 enrolled54 locationsNCT06100289
Recruiting
Phase 3
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Colorectal Neoplasms
Janssen Research & Development, LLC700 enrolled250 locationsNCT06750094
Recruiting
Phase 3
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Colorectal Neoplasms
Janssen Research & Development, LLC1,000 enrolled238 locationsNCT06662786
Recruiting
Not Applicable
A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta
Aortic AneurysmAortic DiseasesAortic Aneurysm and Dissection+3 more
Vascutek Ltd.150 enrolled21 locationsNCT07078383
Recruiting
Phase 3
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
Ovarian Cancer
Incyte Corporation466 enrolled178 locationsNCT07214779
Recruiting
Not Applicable
The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study
Aortic Stenosis
University of Leicester2,104 enrolled110 locationsNCT04204915
Recruiting
Respiratory Muscles in End-stage Lung Disease: Pathophysiological Processes & Clinical Consequences
COPD
University Medical Center Groningen60 enrolled4 locationsNCT06935825
Recruiting
Phase 3
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
Non-small Cell Lung CancerAnaplastic Lymphoma Kinase-positive
Nuvalent Inc.450 enrolled157 locationsNCT06765109
Recruiting
Not Applicable
The TASTY-steering Study
Metastatic Triple-negative Breast CancerMetastatic Testicular CancerStage II-IV Diffuse Large B Cell Lymphoma
University Medical Center Groningen201 enrolled11 locationsNCT07258563
Recruiting
Phase 1Phase 2
Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care
Shock, Cardiogenic
4TEEN4 Pharmaceuticals GmbH90 enrolled25 locationsNCT06832722
Recruiting
Not Applicable
Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation-2 (TELSTAR-2)
comaElectrographic Status Epilepticus
University of Twente150 enrolled21 locationsNCT06549426
Recruiting
Phase 1
A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies
Diffuse Large B-Cell Lymphoma (DLBCL)Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)+6 more
Nurix Therapeutics, Inc.572 enrolled62 locationsNCT05131022
Recruiting
Phase 3
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV220 enrolled10 locationsNCT06451757
Recruiting
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants
Retinitis PigmentosaInherited Retinal Degeneration
Jaeb Center for Health Research1,500 enrolled36 locationsNCT05589714
Recruiting
Phase 2
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease
Primary Mitochondrial Disease
Pharming Technologies B.V.180 enrolled55 locationsNCT05650229
Recruiting
Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)
Myotonic Dystrophy 1DM1
Virginia Commonwealth University700 enrolled17 locationsNCT03981575
Recruiting
Phase 1Phase 2
Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC
PDAC
Anocca AB96 enrolled10 locationsNCT07145450
Recruiting
Phase 3
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Familial Adenomatous Polyposis (FAP)
Rapamycin Holdings Inc.168 enrolled29 locationsNCT06950385
Recruiting
Phase 3
A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease
Crohn's Disease
Takeda396 enrolled138 locationsNCT06227910
Recruiting
Phase 2
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled85 locationsNCT06172478