Clinical Trials in North York, Canada

1 recruiting

Showing 120 of 39 trials

Recruiting
Phase 3

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

ObesityHeart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection Fraction
Amgen5,056 enrolled603 locationsNCT07037459
Recruiting
Phase 3

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

Heart FailureAcute Heart Failure
Colorado Prevention Center5,200 enrolled299 locationsNCT06008197
Recruiting
Not Applicable

Platform of Randomized Adaptive Clinical Trials in Critical Illness

Respiratory InsufficiencyMechanical Ventilation Pressure HighExtracorporeal Membrane Oxygenation Complication
University Health Network, Toronto6,250 enrolled89 locationsNCT05440851
Recruiting
Phase 3

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

Huntington Disease
Novartis Pharmaceuticals770 enrolled10 locationsNCT07326709
Recruiting
Phase 3

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

Cardiovascular Disease
Amgen11,000 enrolled243 locationsNCT07136012
Recruiting
Not Applicable

Modifying PEST for Psoriatic Arthritis Screening

Psoriatic ArthritisPlaque Psoriasis
Novartis Pharmaceuticals502 enrolled21 locationsNCT06382051
Recruiting
Phase 3

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Heart Failure and Impaired Kidney Function
AstraZeneca4,800 enrolled845 locationsNCT06307652
Recruiting
Phase 3

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

Hyperlipidemia
Merck Sharp & Dohme LLC975 enrolled89 locationsNCT07216482
Recruiting
Not Applicable

LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)

Acute Kidney InjuryDialysis; Complications
University of Alberta100 enrolled9 locationsNCT06446739
Recruiting
Phase 2Phase 3

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

StrokeAcute StrokeIschemic Stroke
DiaMedica Therapeutics Inc728 enrolled66 locationsNCT05065216
Recruiting
Phase 3

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

ObesityOverweightAtherosclerotic Cardiovascular Disease
Amgen12,800 enrolled759 locationsNCT07037433
Recruiting

EXtubation Related Complications - the EXTUBE Study (EXTUBE)

Extubation
University Health Network, Toronto3,000 enrolled28 locationsNCT06442930
Recruiting
Phase 3

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

Atherosclerotic Cardiovascular Disease (ASCVD)Elevated Lp(a)
Eli Lilly and Company10,450 enrolled751 locationsNCT07157774
Recruiting
Phase 3

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

Cardiovascular Disease
AstraZeneca15,100 enrolled1264 locationsNCT07000357
Recruiting
Phase 2Phase 3

Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia

Agitation Associated With Alzheimer's Disease Dementia
Exciva GmbH300 enrolled14 locationsNCT07284472
Recruiting
Phase 2

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Aortic Stenosis
Novartis Pharmaceuticals502 enrolled139 locationsNCT05646381
Recruiting
Phase 3

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Heart Failure
AstraZeneca11,300 enrolled928 locationsNCT06677060
Recruiting
Phase 2

A Study Evaluating TRIV-509 in Atopic Dermatitis

Atopic Dermatitis
Triveni Bio90 enrolled44 locationsNCT07167758
Recruiting
Phase 2

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

Alzheimer s Disease
Novartis Pharmaceuticals407 enrolled52 locationsNCT07094516
Recruiting
Phase 4

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Ulcerative Colitis
Takeda65 enrolled49 locationsNCT06095128