Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors

This trial is studying whether delivering immunotherapy and chemotherapy drugs directly into the tumor (through an artery or into the tumor itself) rather than through a vein is more effective for treating advanced solid tumors. **You may be eligible if...** - You have a confirmed diagnosis of advanced cancer (any solid tumor type) - You are 18 years or older with an estimated life expectancy of more than 3 months - Your liver function is within an acceptable range (Child-Pugh A or B) - Your blood counts, kidney, and liver markers are within acceptable thresholds - You have at least one measurable tumor lesion **You may NOT be eligible if...** - You have blood clotting disorders that cannot be corrected - Your organ function is too impaired for the procedure - You are pregnant - You have severe allergies to contrast dye or study medications Talk to your doctor to see if this trial is right for you.