RecruitingNCT03839784

Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient


Sponsor

Stanford University

Enrollment

250 participants

Start Date

Sep 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia. The team plans to build the first of its kind comprehensive database of demographic and risk factor questionnaire responses, biobanked blood specimens, intraoperative electroencephalography (EEG), and inclusive cognitive testing throughout patient interaction starting at the preop appointment until a year later. This will be used to create a predictive model of periooperative neurocognitive disorders.


Eligibility

Min Age: 65 Years

Inclusion Criteria3

  • At least 65 years old (inclusive)
  • Non cardiac general elective surgery
  • General anesthesia is expected for 2+ hours

Exclusion Criteria7

  • Alzheimer's
  • Dementia
  • Parkinson's
  • History of neurodegenerative diseases
  • Medication for depression (ie. Benzodiazepines)
  • Alcoholism
  • Discretion of PI

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Interventions

COMBINATION_PRODUCTNeurocognition Interventions

EEG, Neurocognitive Battery Testing, and Immune Profiles


Locations(1)

Stanford Medical Center

Stanford, California, United States

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NCT03839784


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