Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient
Stanford University
250 participants
Sep 1, 2020
OBSERVATIONAL
Conditions
Summary
The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia. The team plans to build the first of its kind comprehensive database of demographic and risk factor questionnaire responses, biobanked blood specimens, intraoperative electroencephalography (EEG), and inclusive cognitive testing throughout patient interaction starting at the preop appointment until a year later. This will be used to create a predictive model of periooperative neurocognitive disorders.
Eligibility
Inclusion Criteria3
- At least 65 years old (inclusive)
- Non cardiac general elective surgery
- General anesthesia is expected for 2+ hours
Exclusion Criteria7
- Alzheimer's
- Dementia
- Parkinson's
- History of neurodegenerative diseases
- Medication for depression (ie. Benzodiazepines)
- Alcoholism
- Discretion of PI
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Interventions
EEG, Neurocognitive Battery Testing, and Immune Profiles
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03839784