RecruitingNot ApplicableNCT03880422

Nutrition and Exercise Interventions in Reducing Androgen Deprivation Therapy-Induced Obese Frailty in Prostate Cancer Survivors

Nutrition and Exercise Interventions to Reduce Androgen Deprivation Therapy-Induced Obese Frailty in Survivors of Advanced Prostate Cancer


Sponsor

Roswell Park Cancer Institute

Enrollment

50 participants

Start Date

May 2, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

This trial studies how well nutrition and exercise interventions work in reducing androgen deprivation therapy-induced obese frailty in prostate cancer survivors. Individualized nutrition and exercise advice for prostate cancer patients on androgen deprivation therapy may help to reduce obese frailty and change the levels of myokines in blood.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a supervised nutrition and exercise program can help prevent or reverse a condition called "obese frailty" — a combination of excess weight and physical weakness — that commonly develops in prostate cancer survivors receiving hormone-blocking therapy (androgen deprivation therapy or ADT). ADT can cause muscle loss, weight gain, and fatigue over time, and this trial tests whether targeted lifestyle intervention can counter those effects. **You may be eligible if...** - You have been diagnosed with prostate cancer of any stage or grade - You are currently on or have been prescribed continuous hormone-blocking therapy (ADT) for less than 5 years - Your blood counts and organ function are within acceptable ranges **You may NOT be eligible if...** - You have severe bone disease or other conditions that make exercise unsafe - You have uncontrolled medical conditions preventing participation - You are already enrolled in a structured supervised exercise program Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTDietary Intervention

Receive diet plan

OTHEREducational Intervention

Attend educational meeting

BEHAVIORALExercise Intervention

Complete exercise program

OTHERQuality-of-Life Assessment

Ancillary studies

OTHERSurvey Administration

Ancillary studies


Locations(1)

Roswell Park Cancer Institute

Buffalo, New York, United States

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NCT03880422


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