RecruitingNot ApplicableNCT03947697

Improving Glycemic Control With Electrical Stimulation

Improving Glycemic Control With Electrical Stimulation in Mexican-Americans


Sponsor

University of Texas, El Paso

Enrollment

60 participants

Start Date

Aug 9, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels. Subjects will be provided with a standardized diet (55/15/30% CHO/PRO/FAT) prior to collection of pre-intervention data of insulin sensitivity. Individuals will then participate in an 8-week electrical stimulation intervention (30min/day, 3x/week) and randomized into placebo/control, NMES, resistance training combined with NMES (RT +NMES), or resistance training (RT) group (n=15 per group), followed by collection of post-intervention data. The control group will receive electrical stimulation up to sensory level, the NMES group will receive stimulation up to tolerable intensity to induce visible muscle contraction, the RT+ NMES will receive stimulation up to tolerable intensity during resistance training, and the RT group will only receive exercise training. Pre-and post-intervention data includes measurements for body composition, resting metabolic rate, VO2max, insulin sensitivity, and comprehensive blood work.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Overweight/Obese (BMI ≥25)
  • Sedentary Lifestyle: Physical Activity Level<1.4
  • Less than 150min/week of structured Exercise

Exclusion Criteria4

  • Use of anti-hypertensive, lipid-lowering or insulin sensitizing medications
  • Excessive alcohol, drug abuse, smoking
  • Pregnant Women
  • Unwilling to adhere to the study Intervention

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Interventions

DEVICENeuromuscular Electrical Stimulation (Sensory)

Group will receive Electrical Stimulation up to sensory level

DEVICENeuromuscular Electrical Stimulation

Group will receive Electrical Stimulation up to maximum tolerable level

OTHERResistance Training

Group will receive exercise training.


Locations(1)

University of Texas at El Paso

El Paso, Texas, United States

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NCT03947697


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