RecruitingNot ApplicableNCT04033497

Treatment Response Assessment Maps to Delineate Necrosis From Tumor After Stereotactic Radiation in Brain Metastases

Treatment Response Assessment Maps (TRAMs) in the Delineation of Radiation Necrosis From Tumor Progression After Stereotactic Radiation in Patients With Brain Metastases: A Prospective Study

Sponsor

Brigham and Women's Hospital

Enrollment

101 participants

Start Date

Aug 20, 2019

Study Type

INTERVENTIONAL

Conditions

Brain Tumor

Summary

This research study is investigating the value of an imaging study of the brain called an MRI (which stands for magnetic resonance imaging), utilized in unique way, to delineate whether the tumor has recurred or whether radiation changes have occurred after a brain metastasis treated with focused radiation has enlarged.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether special MRI scans can accurately tell the difference between dead tissue (necrosis) and active, living tumor in brain cancer patients after treatment. This distinction is currently very difficult to make but is critical for deciding whether more treatment is needed. **You may be eligible if...** - You have been treated for a brain tumor and have a new or growing area on your MRI that could be either dead tissue or active cancer - You are scheduled for surgery or biopsy to confirm what the area is - You are 18 or older **You may NOT be eligible if...** - You cannot safely undergo an MRI (e.g., certain metal implants) - You are pregnant - You are not a candidate for the follow-up procedures needed in the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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