RecruitingNot ApplicableNCT04234217

Mechanisms of Prediabetic States in Sleep Apnea


Sponsor

University of Chicago

Enrollment

300 participants

Start Date

Nov 26, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to better understand how sleep apnea contributes to the development of diabetes.


Eligibility

Min Age: 20 YearsMax Age: 65 Years

Inclusion Criteria3

  • Overweight or obese
  • Prediabetic
  • Sleep apnea

Exclusion Criteria6

  • Diabetic
  • Severe hypertension
  • Taking medications that can confound assessments
  • Any history of known bleeding disorders
  • Any underlying disease likely to limit life span or increase risk of intervention
  • Currently pregnant, trying to get pregnant or nursing

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Interventions

DEVICEContinuous positive airway pressure

Continuous positive airway pressure (CPAP) treatment of obstructive sleep apnea (OSA)

OTHERNiacin

Suppression of lipolysis by niacin infusion


Locations(1)

University of Chicago

Chicago, Illinois, United States

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NCT04234217


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