Pre-diabetes Clinical Trials

36 recruiting

Pre-diabetes Trials at a Glance

23 actively recruiting trials for pre-diabetes are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Ann Arbor, Aurora, and Baltimore. Lead sponsors running pre-diabetes studies include Arborvitae Health and Wellbeing Pty Ltd, Brightseed, and AdventHealth Translational Research Institute.

Browse pre-diabetes trials by phase

Treatments under study

About Pre-diabetes Clinical Trials

Looking for clinical trials for Pre-diabetes? There are currently 36 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Pre-diabetes trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Pre-diabetes clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting
Not Applicable

OGTT at Home Using CGM vs at the Clinic

DiabetesPre-diabetes
Linkoeping University75 enrolled3 locationsNCT06862128
Recruiting
Phase 4

The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics

ObesityPre-diabetes
Philip Kern96 enrolled1 locationNCT05051436
Recruiting
Phase 2

Long Term Impact of Time-Restricted Eating on Parameters of Cardiometabolic Health

Metabolic SyndromePre-diabetes
University of California, San Diego140 enrolled1 locationNCT07189234
Recruiting
Not Applicable

Lifestyle Patterns and Glycemic Control

Pre-diabetes
Columbia University34 enrolled1 locationNCT05224986
Recruiting
Not Applicable

Continuous Glucose Monitoring (CGM) in Prediabetes

Pre-diabetes
SingHealth Polyclinics76 enrolled2 locationsNCT07371546
Recruiting
Not Applicable

Mechanisms of Prediabetic States in Sleep Apnea

Sleep ApneaPre-diabetes
University of Chicago300 enrolled1 locationNCT04234217
Recruiting
Not Applicable

The GRoceries Aimed at Increasing Nutrition Study

Type 2 Diabetes Mellitus (T2DM)Type 2 DiabetesType 2 Diabetes (T2DM)+6 more
University of Pennsylvania216 enrolled1 locationNCT07167004
Recruiting
Not Applicable

Mechanisms of Fatigability With Diabetes

Type 2 DiabetesPre-diabetes
University of Michigan80 enrolled1 locationNCT04442451
Recruiting
Not Applicable

Timing Exercise Training as Strategy to Improve Insulin Sensitivity and Substrate Metabolism in Men and Woman With Pre-diabetes

Overweight and ObesityPre-diabetes
Maastricht University Medical Center24 enrolled1 locationNCT06014684
Recruiting

UK Islet Autoantibody Registry

ScreeningPre-diabetesType 1 Diabetes (T1D)+1 more
University of Oxford350 enrolled1 locationNCT07125365
Recruiting
Not Applicable

Regular Use of aPDT in the Management and Prevention of Periodontitis Symptoms in Diabetic Patients

Diabetes Mellitus, Type 2Periodontal DiseasesPeriodontitis+1 more
Wellbeing Services County of Pirkanmaa150 enrolled1 locationNCT06486012
Recruiting
Early Phase 1

Breaking up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes

Pre-diabetes
University of Colorado, Denver66 enrolled1 locationNCT05041491
Recruiting
Not Applicable

More Health Less Diabetes

Pre-diabetes
Faculdade de Motricidade Humana90 enrolled1 locationNCT07079722
Recruiting
Not Applicable

Community Engagement Alliance Against Disparities

HypertensionDiabetesOverweight and Obesity+1 more
Johns Hopkins University664 enrolled2 locationsNCT06607341
Recruiting

Toronto Gestational Glucose Tolerance Cohort

Type 2 Diabetes, Gestational Diabetes, Pre-diabetes
Mount Sinai Hospital, Canada350 enrolled1 locationNCT02583061
Recruiting
Not Applicable

The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults

Sedentary BehaviorAgingType 2 Diabetes+2 more
AdventHealth Translational Research Institute50 enrolled1 locationNCT03761446
Recruiting
Not Applicable

Impact of High Fiber and Vegetal Protein Diet on Gut Health and Immunity Biomarkers in Prediabetic Patients

Pre-diabetes
University of Roehampton45 enrolled1 locationNCT06147323
Recruiting

Improving activity-sleep patterns to enhance glucose control in higher risk mid aged adults.

Glucose control (Pre-diabetes)
The University of Newcastle108 enrolled1 locationACTRN12624000811505
Recruiting
Not Applicable

Dietary Supplementation on Body Fat Composition

DyslipidemiasPre-diabetes
Brightseed150 enrolled1 locationNCT06296251
Recruiting

Prevention of Diabetes Progression in Primary Care through Shared Medical Appointments

DiabetesPre-diabetes
NICM, Health Research Institute, University of Western Sydney240 enrolled1 locationACTRN12619001353189