Genetic of Response to Acute Saline Load Test in Hypertension (Naload)

This study is looking at whether genetics plays a role in how people with high blood pressure respond to a salt (saline) challenge — specifically whether their blood pressure reacts differently based on their genes. This could help doctors better personalize blood pressure treatment. **You may be eligible if...** - You are a man between 18 and 65 years old - You have a BMI under 30 - You have high blood pressure (systolic above 140 and diastolic above 90) confirmed at 3 doctor visits - Your salt intake is in a moderate range **You may NOT be eligible if...** - You are female - You have had a heart attack, stroke, or heart failure - You have liver disease, diabetes, or severe high blood pressure (above 160/110) - You have a history of drug or alcohol abuse - You have reduced kidney function - A secondary cause of high blood pressure (like a hormonal disorder) has been identified Talk to your doctor to see if this trial is right for you.