Cocaine Use Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Cocaine Use clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 118 of 18 trials

Recruiting
Phase 2

Repurposing Semaglutide for the Treatment of Cocaine Use Disorder

Cocaine Use Disorder
The University of Texas Health Science Center, Houston75 enrolled1 locationNCT07227948
Recruiting
Not Applicable

Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder

Substance Use Disorder (SUD)Cocaine Use DisorderCocaine Dependence
Icahn School of Medicine at Mount Sinai120 enrolled1 locationNCT07318480
Recruiting
Phase 4

Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder

Cocaine Use DisorderCrack Abuse or Dependence
University of Sao Paulo General Hospital36 enrolled1 locationNCT07313371
Recruiting
Not Applicable

Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder

Substance Use Disorder (SUD)Alcohol Use Disorder (AUD)Cocaine Use Disorder (CUD)
University of Bern210 enrolled1 locationNCT07071779
Recruiting
Not Applicable

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

Opioid UseOpioid-use DisorderSubstance Use+2 more
Wake Forest University Health Sciences600 enrolled2 locationsNCT04927143
Recruiting
Early Phase 1

Safety Profile of Psilocybin for Cocaine Use Disorder

Cocaine Use Disorder
University of California, Los Angeles10 enrolled1 locationNCT06102434
Recruiting
Not Applicable

CRACK-TARGET 1: Descriptive Study of Observed Behavioral Sensitization and Expectations

Cocaine Use Disorder
Assistance Publique - Hôpitaux de Paris20 enrolled2 locationsNCT06050304
Recruiting
Not Applicable

A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder

Training for Cocaine Use Disorder
ASST Fatebenefratelli Sacco60 enrolled1 locationNCT07033416
Recruiting
Early Phase 1

Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)

Cocaine Use Disorder
William Stoops24 enrolled2 locationsNCT05610072
Recruiting
Early Phase 1

Cocaine and Pentoxifylline (BED IN 47)

Cocaine Use Disorder
William Stoops30 enrolled1 locationNCT07086794
Recruiting

Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study

Cocaine Use Disorder
Yale University80 enrolled1 locationNCT04721418
Recruiting
Phase 2

Evaluation Of Semaglutide in Adults With Cocaine Use Disorder With and Without HIV

HIVCocaine Use Disorder
University of Maryland, Baltimore40 enrolled2 locationsNCT06691243
Recruiting
Not Applicable

Cocaine Cue-reactivity Incubation Study

Cocaine Use Disorder
Icahn School of Medicine at Mount Sinai252 enrolled1 locationNCT07091877
Recruiting
Early Phase 1

[C-11]NPA PET-amphetamine in Cocaine Use Disorders

Cocaine Use Disorder
Rajesh Narendran30 enrolled1 locationNCT05011760
Recruiting
Early Phase 1

Imaging CRF X NOP Interactions in CUD

Cocaine Use Disorder
Rajesh Narendran80 enrolled1 locationNCT05008146
Recruiting
Not Applicable

Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder

Cocaine Use Disorder
The University of Texas Health Science Center, Houston75 enrolled1 locationNCT05986578
Recruiting
Phase 2

Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction

Cocaine Use DisorderCocaine Dependence
Dr. med. Marcus Herdener120 enrolled1 locationNCT06125054
Recruiting
Not Applicable

Innovative Cognitive and Behavioral Psychotherapy for Cocaine Use Disorder

Cocaine Use Disorder
Thomas Lehoux54 enrolled2 locationsNCT05833529