RecruitingNCT05169177

Radio-opaque Contrast Agents for Liver Cancer Targeting With KIM During Radiation Therapy


Sponsor

University of Sydney

Enrollment

50 participants

Start Date

Oct 17, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This observational study will investigate the properties of image files standardly collected during radiation therapy treatment in a cross-section of liver cancer patients who received stereotactic ablative body radiation therapy (SABR) after trans-catheter arterial chemo emobilisation (TACE). Specifically, it will determine whether the radio-opaque contrast agents in the image files can be detected by tumour-tracking software (KIM).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a technology called KIM (Kilovoltage Intrafraction Monitoring) that tracks a radio-opaque marker (a visible substance previously placed in the liver during a prior procedure) during radiation therapy for liver cancer — to better target the tumor and avoid harming healthy tissue. **You may be eligible if...** - You have liver cancer and are receiving (or have received) stereotactic ablative body radiotherapy (SABR) at a participating site - A radio-opaque contrast agent (such as Lipiodol or DC Bead LUMI) is visible on your radiation planning CT scan and will be in the imaging field during treatment - You are 18 years of age or older **You may NOT be eligible if...** - You are under 18 years of age - The required image data is not available or is in an incompatible format Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(5)

Calvary Mater Newcastle Hospital

Waratah, New South Wales, Australia

Westmead Hospital

Westmead, New South Wales, Australia

Princess Alexandra Hospital

Woolloongabba, Queensland, Australia

Peter MacCallum Cancer Centre

Melbourne, Victoria, Australia

The Austin Hospital

Melbourne, Victoria, Australia

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NCT05169177


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