RecruitingNot ApplicableNCT05553223

Micro-doses of Physical Activity for COPD

Can Micro-doses of Physical Activity Offset the Negative Cardiovascular Consequences of Being Sedentary in Patients With COPD?

Sponsor

University of British Columbia

Enrollment

20 participants

Start Date

Oct 12, 2022

Study Type

INTERVENTIONAL

Conditions

Cardiovascular Diseases Hypertension Chronic Obstructive Pulmonary Disease Endothelial Dysfunction Vascular Stiffness

Summary

Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than healthy individuals. Those who are the most sedentary have a greater risk of heart and blood vessel disease, which may lead to an early death. This project will investigate the effect of sitting still for 3 hours on blood vessel health in individuals with COPD. It will also investigate whether breaking up the amount of time patients sit with regular short bouts of walking (5 minutes each hour) at a comfortable pace chosen by the patient can have a positive effect on maintaining the health of their blood vessels. It is hypothesized that blood vessel health will be worse after 3 hours of sitting compared to when the sitting is broken up by short bouts of walking.

Eligibility

Plain Language Summary

Simplified for easier understanding

This study is testing whether short bursts of physical activity ("micro-doses") throughout the day can help people with moderate-to-severe COPD (a chronic lung disease) stay more active and breathe better. **You may be eligible if:** - You have been diagnosed with moderate-to-severe COPD - You stopped smoking at least 6 months ago - Your condition has been stable for at least 6 weeks (no recent flare-ups) **You may NOT be eligible if:** - You are already doing structured exercise or pulmonary rehabilitation - You have a history of deep vein thrombosis (blood clots in the legs) - You take blood-thinning medication - You have serious heart or stroke-related disease (such as heart failure, prior stroke, or prior heart attack) - You have diabetes - You have joint or muscle problems that prevent physical activity - Researchers cannot get a clear ultrasound reading of your blood vessels Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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