Studying the Effects of Cannabis on Vasculature
Elucidating the Effects of Cannabis on Cardiovascular System
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
100 participants
Dec 1, 2023
OBSERVATIONAL
Conditions
Summary
Cannabis is commonly used globally. It is associated with psychiatric problems, but the effects on the cardiovascular system are unclear. In this project, the investigators plan to study the effects of cannabis on the cardiovascular system. This will be done by using a non-invasive test to measure blood vessel function and by using blood samples to measure inflammation. As a control for this project, the investigators would like to test the blood vessel function and inflammation levels of participants who do not use cannabis. This study will provide important information on the long term cardiovascular effects of cannabis.
Eligibility
Inclusion Criteria6
- age: 19 to 80
- males and females
- all ethnicities
- cannabis use at least 3-4 times per week or more in the past 6 months (50 volunteers, experimental group)
- patients who do not use cannabis (50 volunteers, control group)
- no history of cardiovascular disease
Exclusion Criteria3
- that ingest cannabis containing cannabidiol (CBD)
- that are unable to provide a receipt for the cannabis product(s) they ingest
- that are unwilling to stop consuming soy products and/or genistein 48 hours prior to appointments.
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Interventions
The investigators will test levels of inflammation and vascular dysfunction in participants who chronically use cannabis.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05581368