RecruitingNot ApplicableNCT05699525

Personalized Mobile Cognitive Behavioral Therapy Application

Efficacy of Personalized Mobile Cognitive Behavioral Therapy Targeting Anxiety and Depression


Sponsor

Weill Medical College of Cornell University

Enrollment

100 participants

Start Date

Aug 2, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to compare the effectiveness of a standard mobile iPhone cognitive behavioral therapy program to a personalized mobile iPhone cognitive behavioral therapy program that introduces new skills over a shorter period of time. Participants will use the Maya app for two days per week, at least 20 minutes per day, for six weeks. Assessments will include a weekly check in with a member of the research team, questionnaires, and optional magnetic resonance imaging (MRI) and electroencephalographic (EEG) recordings at the beginning and end of the 6-week intervention. The investigators think that that the less burdensome personalized program will be just as effective at improving symptoms of anxiety and depression as the general program.


Eligibility

Min Age: 18 YearsMax Age: 25 Years

Inclusion Criteria4

  • Age between 18 and 25 years.
  • Primary diagnosis of an anxiety, depressive, or bipolar disorder as determined by a score of 4 or greater on the Clinical Severity Rating of the Anxiety Disorders Interview Schedule (ADIS).
  • If an individual is diagnosed with bipolar disorder, they must be currently euthymic or experiencing a depressive episode.
  • Access to an Apple iPhone

Exclusion Criteria7

  • History of neurologic disorder that may affect the neural systems of interest or participant's ability to participate
  • Lifetime diagnosis of a psychotic disorder.
  • Current hypomanic or manic episode.
  • Currently in cognitive behavior therapy.
  • Change in dose of a psychiatric medication in the past 12 weeks.
  • Initiation of psychotherapy in the past 12 weeks.
  • Intent or plan to attempt suicide.

Interventions

BEHAVIORALPersonalized MAYA Mobile App

All new material in the personalized condition will be introduced within the first four weeks and will contain modules targeting participant's personal symptom profiles. The remaining two weeks in the personalized condition will consist of practicing previously learned skills.

BEHAVIORALGeneral MAYA Mobile App

New material will be introduced to participants over all the six weeks of the intervention and will include all application modules.


Locations(1)

Weill Cornell Medical College

New York, New York, United States

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NCT05699525


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