Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer.

This study is testing whether a mouth guard-like device called a mandibular advancement device (MAD) — which gently holds the jaw forward during sleep to keep the airway open — can reduce snoring and sleep apnea in patients who have been treated with radiation for oropharyngeal cancer (cancer of the throat/tonsils). Radiation can alter the throat anatomy and contribute to sleep breathing problems. **You may be eligible if...** - You have been diagnosed with oropharyngeal cancer and received radiation therapy - You are 18 or older (predominantly male patients expected) - You have complaints of snoring and/or breathing pauses during sleep **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have too few teeth remaining to support the device - You are taking opioid or anxiety medications - You have a history of major depression, uncontrolled high blood pressure, or prior stroke - You are already using a CPAP machine for sleep apnea - You have significant daily jaw or facial pain - You have excessive alcohol or drug use Talk to your doctor to see if this trial is right for you.