Sleep and Metabolism
Uncovering Sleep and Circadian Mechanisms Contributing to Adverse Metabolic Health
Oregon Health and Science University
20 participants
Dec 1, 2023
INTERVENTIONAL
Conditions
Summary
The goal of this study is to uncover sleep and circadian mechanisms contributing to adverse metabolic health. The protocol is a 21 day (7 outpatient days, 14 inpatient days) mechanistic randomized-crossover study designed to identify the impact of chronic sleep restriction and circadian timing, independently and in combination on energy metabolism and identify the independent and combined effects on glucose tolerance.
Eligibility
Plain Language Summary
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Interventions
Participants are randomized into either a group (n=10) that is sleep restricted first or control first (n=10) group; the groups will crossover halfway through the protocol. Both arms are fed 3 meals and have access to ad libitum food between meals. Both groups will also undergo up to 3 mixed-meal tolerance tests to measure glucose tolerance.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05775627