Weight Gain Clinical Trials

44 recruitingLast updated: June 17, 2026

There are 44 actively recruiting weight gain clinical trials across 21 countries. Studies span Not Applicable, Phase 2, Phase 3, Early Phase 1. Top locations include Ann Arbor, Michigan, United States, London, Ontario, Canada, Buffalo, New York, United States. Updated daily from ClinicalTrials.gov.


Weight Gain Trials at a Glance

44 actively recruiting trials for weight gain are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Ann Arbor, London, and Buffalo. Lead sponsors running weight gain studies include University of Michigan, University of Arkansas, and Johns Hopkins University.

Browse weight gain trials by phase

Treatments under study

About Weight Gain Clinical Trials

Looking for clinical trials for Weight Gain? There are currently 19 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Weight Gain trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Weight Gain clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 44 trials

Recruiting
Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Weight GainHealthy VolunteerMetabolic Effects+1 more
National Institute of Allergy and Infectious Diseases (NIAID)120 enrolled1 locationNCT05652478
Recruiting
Not Applicable

Healthy for Two-Home Visiting (H42-HV): Health Coaching for Pregnant Women

Overweight and ObesityBehavior, HealthPregnancy weight gain+1 more
Johns Hopkins University360 enrolled1 locationNCT05619705
Recruiting
Not Applicable

Exercise Effects on Adipose Tissue Structure and Function

ObesityInsulin ResistanceWeight Loss+3 more
University of Michigan46 enrolled1 locationNCT04812314
Recruiting
Phase 3

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

ObesityWeight Gain
Eli Lilly and Company300 enrolled73 locationsNCT06439277
Recruiting

Fluid Intake After Hemodialysis

Chronic Kidney Disease Requiring Chronic DialysisInterdialytic Weight Gain
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's20 enrolled2 locationsNCT04721652
Recruiting
Not Applicable

DIStal gastriC Bypass OUtcome in Revision SurgEry After Roux-en-y Gastric Bypass

Weight GainObesity, Morbid
St. Antonius Hospital150 enrolled8 locationsNCT04894838
Recruiting

Effect of Gestational Weight Gain on Spinal Anesthesia in Elective Cesarean Delivery

cesarean deliveryRegional AnesthesiaGestational Weight Gain
Elazıg Fethi Sekin Sehir Hastanesi200 enrolled1 locationNCT07326644
Recruiting
Early Phase 1

A Study of Niacin Regulation

Excessive Weight Gain
Mayo Clinic32 enrolled1 locationNCT06175403
Recruiting
Not Applicable

The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer

Breast CancerInsomniaWeight Gain
Johns Hopkins University250 enrolled4 locationsNCT05780814
Recruiting

Determinant Factors in Excessive Gestational Weight Gain: Physical Activity, Nutritional Status, and Anxiety

PregnancyExcessive Gestational Weight Gain
Bezmialem Vakif University150 enrolled1 locationNCT07368465
Recruiting
Phase 2

Incretin Microdosing for Cardiometabolic Health in People With HIV

Weight Gain
The University of Texas Health Science Center, Houston30 enrolled1 locationNCT07325500
Recruiting
Not Applicable

Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women

PregnancyWeight Gain
University of Michigan570 enrolled1 locationNCT05000645
Recruiting
Not Applicable

Effects of the Mediterranean Diet During Pregnancy on the Onset of Allergies in the Offspring

ObesityAllergiesChronic Diseases in Children+5 more
Federico II University276 enrolled2 locationsNCT05119868
Recruiting
Not Applicable

Time-restricted Eating Among Pregnant Females With Severe Obesity

Time Restricted EatingObesity, MorbidPregnancy weight gain
University of Illinois at Chicago60 enrolled1 locationNCT06477120
Recruiting
Not Applicable

Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0

PregnancyOverweight and ObesityGestational Weight Gain+1 more
Penn State University144 enrolled1 locationNCT05807594
Recruiting
Not Applicable

Time Restricted Eating for WeIght LoSs MainTenance-2

Weight LossWeight GainWeight Loss Maintenance
NYU Langone Health110 enrolled1 locationNCT07190170
Recruiting
Not Applicable

The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)

Blood PressureWeight GainInsulin Sensitivity+2 more
Arkansas Children's Hospital Research Institute150 enrolled2 locationsNCT05992688
Recruiting
Not Applicable

BEP Targeting Strategies in Ethiopia

neonatal deathPreterm BirthSmall for Gestational Age at Delivery+5 more
Harvard School of Public Health (HSPH)6,750 enrolled1 locationNCT06125860
Recruiting
Not Applicable

LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers

ObesityBody WeightLife Style, Healthy+2 more
Odense University Hospital301 enrolled1 locationNCT05774652
Recruiting
Not Applicable

Cessation of Dual Use of Cigarettes and E-cigarettes During Pregnancy

Gestational Weight GainDual Use of Cigarettes and E-cigarettesBirth-weight-for-gestational-age z Score
State University of New York at Buffalo45 enrolled1 locationNCT07124702