RecruitingPhase 1NCT05873699

Study Using Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging in Patients With Pancreatic Cysts Undergoing Surgical Resection

Pilot Study Using Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging in Patients With Pancreatic Cysts Undergoing Surgical Resection

Sponsor

M.D. Anderson Cancer Center

Enrollment

20 participants

Start Date

Aug 18, 2023

Study Type

INTERVENTIONAL

Conditions

Pancreatic Cyst

Summary

To learn if Hyperpolarized C-Pyruvate Magnetic Resonance (HP-MR) Spectroscopic Imaging can help doctors detect low-risk (benign) and high-risk (malignant) cysts.

Eligibility

Min Age: 18 Years

Inclusion Criteria5

Patients ≥ 18 years old. Patients under 18 are excluded due to their potential inability to understand and consent independently to the methods required for the study drug use and its potential risks and benefits.
Patients with pancreatic cyst/s
Patients who will undergo surgical resection (or cyst wall biopsy) of pancreatic cysts
Patients able to understand and willing to sign a written informed consent document
Both English-speaking and non-English-speaking patients are eligible for participation

Exclusion Criteria8

Contraindication to MRI
Electrically, magnetically, or mechanically activated implants that would preclude MRI
Allergy to Gadavist IV contrast
History of cardiac arrhythmias
Pregnancy or breastfeeding women
Women of child-bearing age that are sexually active and not using birth control
Cognitively impaired individuals
Weight above 260 pounds (lbs)