Hyperpolarized C Pyruvate Magnetic Resonance Imaging, and Blood-Based Biomarkers for Early Detection of Pancreatic Adenocarcinoma in Patients With Intraductal Papillary Mucinous Neoplasms

This study uses a specialized MRI scan with a special carbon-based agent (hyperpolarized pyruvate) and blood tests to try to detect early signs of pancreatic cancer in people who have high-risk cysts in their pancreas (called intraductal papillary mucinous neoplasms, or IPMNs). **You may be eligible if...** - You are over 18 years old - You have a pancreatic cyst that your doctors have classified as high-risk, requiring surgical removal - You can provide informed consent **You may NOT be eligible if...** - You already have a confirmed diagnosis of pancreatic cancer - You are pregnant or breastfeeding - You are unable or unwilling to undergo MRI scanning (for example, due to claustrophobia or inability to lie flat) - Your liver function tests (bilirubin, ALT/AST, albumin) are outside acceptable ranges Talk to your doctor to see if this trial is right for you.